Acute Coronary Syndromes: A Companion to Braunwald's Heart Disease Book

	Foreword	xiii
	Preface	xv
Section 1	Acute Coronary Syndromes and Clinical Practice	1
1	From Pre-infarction Angina to Acute Coronary Syndromes: A Historical Perspective	1
2	Acute Coronary Syndromes: National and International Dimensions of the Problem	10
3	An Epidemiological Perspective: Society, Environment, Risk Factors, and Genetics	15
4	Natural History and Prognosis	49
Section 2	Pathophysiology	67
5	Pathology of Stable and Acute Coronary Syndromes	67
6	Molecular Mechanisms of the Acute Coronary Syndromes: The Roles of Inflammation and Immunity	80
7	The Role of Infection	88
8	Triggers to Acute Coronary Syndromes	108
9	Novel Risk Factors in Acute Coronary Syndromes	119
10	What Cardiologists Need to Know on Depression in Acute Coronary Syndromes	131
Section 3	Diagnosis	145
11	Clinical Recognition of Acute Coronary Syndromes	145
12	Acute Coronary Syndromes in the Emergency Department: Diagnosis, Risk Stratification, and Management	152
13	Electrocardiography, ECG Monitoring, and Provocative Stress Testing in Acute Coronary Syndromes	168
14	Biochemical Markers of Myocardial Necrosis	187
15	Markers of a Thrombotic State	197
16	Markers of Inflammation	209
17	Coronary Angiography and the Culprit Lesion in Acute Coronary Syndromes	226
18	Echocardiography in Acute Coronary Syndromes	250
19	Nuclear Cardiology Techniques in Acute Coronary Syndromes	269
20	Computed Tomography in Coronary Artery Disease	285
21	Emerging Diagnostic Procedures for the Vulnerable Plaque	294
22	Risk Stratification in Non-ST-Segment Elevation Acute Coronary Syndromes	308
23	Continuous Risk Stratification	322
Section 4	Pharmacologic Management	331
24	Nitrates and Nitric Oxide Donors	331
25	[beta]-Blockers and Calcium Channel Blockers: Use in Acute Coronary Syndromes	341
26	ATP-Sensitive Potassium Channels, Adenosine, and Preconditioning	351
27	Metabolic Interventions	359
28	Antiplatelet Therapy	368
29	Anticoagulant Therapy	400
Section 5	Management Strategies	419
30	Acute Plaque Passivation and Endothelial Therapy	419
31	Anti-thrombotic Management	431
32	Treatment of Cardiovascular Inflammation	444
33	Myocardial Cell Protection in Acute Coronary Syndromes	453
Section 6	Revascularization	473
34	Revascularization in Acute Coronary Syndromes: Which Patients and When?	473
35	Advantages and Hazards of Early Revascularization	492
36	New Surgical and Percutaneous Revascularization Procedures	498
37	Pharmacologic Revascularization	515
38	The Patient with Disabling Angina Not Amenable to Revascularization Procedures	539
Section 7	Special Subgroups	553
39	The Elderly, Women, and Patients with Diabetes Mellitus	553
40	Coronary Artery Spasm	574
41	The Patient with Chest Pain Despite Normal Coronary Angiography	588
42	Cocaine and Other Environmental Causes of Acute Coronary Syndromes	594
Section 8	From the Acute Phase to the Chronic Phase	601
43	Control of Risk Factors	601
44	Dietary Intervention in Coronary Care Units and in Secondary Prevention	613
Section 9	Outlook to the Future	633
45	Perspective for Gene and Cell-Based Therapy	633
46	Cardiovascular Regeneration and Stem Cell Differentiation	649
47	Identifying the Vulnerable Plaque and the Vulnerable Patient	661
48	The Modern Coronary Care Unit	677
Section 10	Guidelines for Management	689
49	Guidelines of the European Society of Cardiology	689
50	ACC/AHA 2002 Guidelines Update for the Management of Patients with Unstable Angina and Non-ST-Segment Elevation Myocardial Infarction--Summary Article	709
	Index	719