Practical Transfusion Medicine Book

1	Introduction	3
2	Essential immunology for transfusion medicine	13
3	Human blood group systems	24
4	Human leucocyte antigens	34
5	Platelet and neutrophil antigens	50
6	The effective and safe use of blood components	67
7	Bleeding associated with trauma and surgery	86
8	Prenatal and childhood transfusions	97
9	Haematological disease	119
10	Transfusion strategies in organ transplant patients	132
11	Inherited and acquired coagulation disorders	138
12	Uses of intravenous immunoglobulin	151
13	Haemolytic transfusion reactions	161
14	Febrile reactions and transfusion-related acute lung injury	171
15	Urticarial and anaphylactic reactions	179
16	Bacterial contamination	184
17	Post-transfusion purpura	191
18	Immunomodulation and graft-versus host disease	195
19	Transfusion-transmitted infections	208
20	Variant Creutzfeldt-Jakob disease	229
21	Donors and blood collection	241
22	Blood donation testing and the safety of the blood supply	250
23	Production and storage of blood components	259
24	Medicolegal aspects	274
25	Blood transfusion in hospitals	280
26	Autologous transfusion	298
27	Tissue banking	309
28	Cord blood banking	320
29	Therapeutic apheresis	328
30	Blood substitutes	341
31	Cytokines in transfusion practice	350
32	Haemopoietic stem cell processing and storage	357
33	Haemopoietic stem cell transplantation and immunotherapy	369
34	Gene therapy	390
35	Recombinant antibodies and other proteins	403
36	Blood transfusion in a global context	415
37	The design of interventional trials in transfusion medicine	424
38	Getting the most out of the evidence for transfusion medicine	436
39	The future of transfusion medicine	445