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Signal Transduction and Cardiac Hypertrophy Book

Signal Transduction and Cardiac Hypertrophy
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  • Signal Transduction and Cardiac Hypertrophy
  • Written by author Naranjan S. Dhalla
  • Published by Springer-Verlag New York, LLC, June 2008
  • A collection of 35 contributions selected from talks presented at the World Heart Congress held in July 2001 in Winnipeg, Canada. Written by leading world experts in the fields of cellular signaling and cardiac hypertrophy, the volume is organized into th
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Dedication: A Tribute to Dr. Jutta Schaper
Preface
Acknowledgments
1Molecular Changes of the Myocardium After Mechanical Circulatory Support3
2Reverse Molecular Remodeling of the Failing Human Heart Following Support with a Left Ventricular Assist Device19
3Stretch-Elicited Autocrine/Paracrine Mechanism in the Heart37
4L-Arginine at the Crossroads of Biochemical Pathways Involved in Myocardial Hypertrophy49
5Signal Transduction System in Human Aortic Smooth Muscle Cell Stimulated by Pure Pressure57
6Role of Mitochondrial K[subscript ATP] Channels in Improved Ischemic Tolerance of Chronically Hypoxic Adult and Immature Hearts69
7Ca[superscript 2+]-Dependent Signaling Pathways Through Calcineurin and Ca[superscript 2+]/Calmodulin-Dependent Protein Kinase in Development of Cardiac Hypertrophy85
8Calreticulin, Cardiac Development and Congenital Complete Heart Block in Children95
9Expression of Sodium-Calcium Exchanger Genes in Heart and Skeletal Muscle Development. Evidence for a Role of Adjacent Cells in Regulation of Transcription and Splicing
10Na[superscript +]/H[superscript +] Exchanger and Myocardial Hypertrophy125
11Role of the Electrogenic Na[superscript +]/HCO[subscript 3] Symport in the Heart139
12Modulation of Atrial Natriuretic Peptide (ANP)-C Receptor and Associated Signaling by Vasoactive Peptides149
13RAB3 Small GTP-Binding Proteins: Regulation by Calcium/Calmodulin167
14Novel Aspects of Mechanical Signaling in Cardiac Tissue181
15Caspase Activation in a Cardiac Cell-Free Model of Apoptosis
16The Role of the Voltage-Sensitive Release Mechanism in Contraction of Normal and Diseased Heart207
17Role of AT[subscript 1] Receptor Blockade in Reperfused Myocardial Infarction221
18Relation Between Intracelluar Ca[superscript 2+] Concentration and Contraction in Tetanized Myocyctes of Rat and Mouse237
19The Role of Hydrogen Peroxide as a Signaling Molecular249
20Localized Control of Oxidative Phosphorylation within Intracellular Energetic Units in Heart Cells: A Possible Solution of Some Old Problems
21Role of High Molecular Weight Calmodulin Binding Protein in Cardiac Muscle285
22[beta]-Adrenergic Signaling in Chronic Heart Failure - Friend or Foe?303
23Compartmentation to Lipid Rafts as a Mechanism to Regulate [beta]-Adrenergic Receptor Signaling in Cardiomycytes323
24Role of Renin-Angiotensin System in Phospholipase C-Mediated Signaling in Congestive Heart Failure335
25JAK/Stat Signaling in Cardiac Diseases349
26Signaling Pathways Involved in the Stimulation of DNA Synthesis by Tumor Necrosis Factor and Lipopolysaccharide in Chick Embryo Cardiomyocytes
27The Application of Genetic Mouse Models to Elucidate a Role for Fibroblast Growth Factor-2 in the Mammalian Cardiovascular System373
28Interaction of COUP-TF II With the Rat Carnitine Palmitoyltransferase I B Promoter in Neonatal Rat Cardiac Myocytes393
29Altered Expression of Conventional Calpains Influences Apoptosis403
30KLF5/BTEB2, a Kruppel-Like Transcription Factor, Regulates Smooth Muscle Phenotypic Modulation
31Transgenic Manipulation of SERCA and PLB Levels and Their Effect on Cardiac Contractility425
32Expression of Vascular Endothelial Growth Factor and Hypoxia-Inducible Factor 1[alpha] in the Myocardium439
33Gene-Based Therapy of Advanced Heart Failure Secondary to the Disruption of Dystrophin-Related Proteom449
34Adaptation to Ischemia by In Vivo Exposure to Hyperoxia-Signalling Through Mitogen Activated Protein Kinases and Nuclear Factor Kappa B461
35The SERCA2 Gene: Genomic Organization and Promoter Characterization479
Index497


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