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Evolving Methods for Macromolecular Crystallography: The Structural Path to the Understanding of the Mechanism of Action of Cbrn Agents Book

Evolving Methods for Macromolecular Crystallography: The Structural Path to the Understanding of the Mechanism of Action of Cbrn Agents
Evolving Methods for Macromolecular Crystallography: The Structural Path to the Understanding of the Mechanism of Action of Cbrn Agents, This volume draws on the expertise of leaders in the field of macromolecular crystallography to illuminate the dramatic developments that are accelerating progress in structural biology. Their contributions span the range of techniques from crystallizatio, Evolving Methods for Macromolecular Crystallography: The Structural Path to the Understanding of the Mechanism of Action of Cbrn Agents has a rating of 3 stars
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Evolving Methods for Macromolecular Crystallography: The Structural Path to the Understanding of the Mechanism of Action of Cbrn Agents, This volume draws on the expertise of leaders in the field of macromolecular crystallography to illuminate the dramatic developments that are accelerating progress in structural biology. Their contributions span the range of techniques from crystallizatio, Evolving Methods for Macromolecular Crystallography: The Structural Path to the Understanding of the Mechanism of Action of Cbrn Agents
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  • Evolving Methods for Macromolecular Crystallography: The Structural Path to the Understanding of the Mechanism of Action of Cbrn Agents
  • Written by author Joel L. Sussman
  • Published by Springer-Verlag New York, LLC, March 2008
  • This volume draws on the expertise of leaders in the field of macromolecular crystallography to illuminate the dramatic developments that are accelerating progress in structural biology. Their contributions span the range of techniques from crystallizatio
  • X-ray crystallography is the pre-eminent technique for visualizing the structures of macromolecules at atomic resolution. These structures are central to understanding the detailed mechanisms of biological processes, and to discovering novel therapeutics
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Authors

Preface

1 Succeeding with Seeding: Some Practical Advice Terese Bergfors Bergfors, Terese 1

2 Expression, Purification, and Crystallisation of Membrane Proteins Bernadette Byrne Byrne, Bernadette 11

3 Macromolecular Cryo-Crystallography Elspeth Garman Garman, Elspeth 25

4 Processing Diffraction Data with Mosflm Andrew G.W. Leslie Leslie, Andrew G. W. Harold R. Powell Powell, Harold R. 41

5 Sad Phasing: Basic Concepts and High-Throughput George M. Sheldrick Sheldrick, George M. 53

6 Likelihood-Based Experimental Phasing in Phaser Airlie J. McCoy McCoy, Airlie J. Laurent C. Storoni Storoni, Laurent C. Randy J. Read Read, Randy J. 67

7 Stochastic Molecular Replacement Nicholas M. Glykos Glykos, Nicholas M. 79

8 Likelihood-Based Molecular Replacement in Phaser Randy J. Read Read, Randy J. Airlie J. McCoy McCoy, Airlie J. Laurent C. Storoni Storoni, Laurent C. 91

9 Automated Structure Determination with Phenix Paul D. Adams Adams, Paul D. Pavel V. Afonine Afonine, Pavel V. Ralf W. Grosse-Kunstleve Grosse-Kunstleve, Ralf W. Nigel W. Moriarty Moriarty, Nigel W. Nicholas K. Sauter Sauter, Nicholas K. Peter H. Zwart Zwart, Peter H. Kreshna Gopal Gopal, Kreshna Thomas R. Ioerger Ioerger, Thomas R. Lalji Kanbi Kanbi, Lalji Erik McKee McKee, Erik Reetal K. Pai Pai, Reetal K. Li-Wei Hung|cThiru Radhakannan Radhakannan, Li-Wei Hung|cThiru Airlie J. McCoy McCoy, Airlie J. Randy J. Read Read, Randy J. Laurent C. Storoni Storoni, Laurent C. Tod D. Romo Romo, Tod D. James C. Sacchettini Sacchettini, James C. Thomas C. Terwilliger Terwilliger, Thomas C. 101

10 Density Modification in Main Dusan Turk Turk, Dusan 111

11 Ab Initio Phasing Starting from Low Resolution VladimirLunin Lunin, Vladimir Natalia Lunina Lunina, Natalia Alexandre Urzhumtsev Urzhumtsev, Alexandre 123

12 Structural Genomics of Mycobacterium Tuberculosis: A Search for Function and New Drug Targets Ted Baker Baker, Ted 135

13 Three-Dimensional Domain Swapping and its Relevance to Conformational Diseases Mariusz Jaskolski Jaskolski, Mariusz 145

14 Structural Bioinformatics: From Protein Structure to Function James D. Watson Watson, James D. Adel Golovin Golovin, Adel Roman A. Laskowski Laskowski, Roman A. Kim Henrick Henrick, Kim Janet M. Thornton Thornton, Janet M. Andrzej Joachimiak Joachimiak, Andrzej Aled M. Edwards Edwards, Aled M. 165

15 Single-Particle Imaging David Sayre Sayre, David 181


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Evolving Methods for Macromolecular Crystallography: The Structural Path to the Understanding of the Mechanism of Action of Cbrn Agents, This volume draws on the expertise of leaders in the field of macromolecular crystallography to illuminate the dramatic developments that are accelerating progress in structural biology. Their contributions span the range of techniques from crystallizatio, Evolving Methods for Macromolecular Crystallography: The Structural Path to the Understanding of the Mechanism of Action of Cbrn Agents

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Evolving Methods for Macromolecular Crystallography: The Structural Path to the Understanding of the Mechanism of Action of Cbrn Agents, This volume draws on the expertise of leaders in the field of macromolecular crystallography to illuminate the dramatic developments that are accelerating progress in structural biology. Their contributions span the range of techniques from crystallizatio, Evolving Methods for Macromolecular Crystallography: The Structural Path to the Understanding of the Mechanism of Action of Cbrn Agents

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Evolving Methods for Macromolecular Crystallography: The Structural Path to the Understanding of the Mechanism of Action of Cbrn Agents, This volume draws on the expertise of leaders in the field of macromolecular crystallography to illuminate the dramatic developments that are accelerating progress in structural biology. Their contributions span the range of techniques from crystallizatio, Evolving Methods for Macromolecular Crystallography: The Structural Path to the Understanding of the Mechanism of Action of Cbrn Agents

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