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Section I | Fundamentals of DHPLC | |
Chapter 1 | Basics of automated, high-accuracy mutation screening with the WAVE Nucleic Acid Fragment Analysis Systems | 15 |
Chapter 2 | Influence of PCR on DHPLC Polymorphism Characterization | 35 |
Section II | Gene Specific Applications of Mutation Detection by DHPLC | |
Chapter 3 | Denaturing High Performance Liquid Chromatography (DHPLC), an important mutation detection technique in mutation analysis of the breast and ovarian cancer predisposing genes BRCA1 and BRCA2 | 53 |
Chapter 4 | Mutation detection in the tuberous sclerosis genes TSC1 and TSC2 by DHPLC | 79 |
Chapter 5 | Rapid analysis to detect base changes in human mitochondrial DNA by restriction enzyme analysis followed by denaturing high performance liquid chromatography | 93 |
Chapter 6 | Mutation analysis of LDLR mutations in patients with familial hypercholesterolaemia | 117 |
Section III | Novel and Innovative Applications of DHPLC | |
Chapter 7 | Novel DHPLC based strategy for identification and characterization of (bi)-clonal T-cell receptor targets for the detection of minimal residual disease in childhood acute lymphoblastic leukemia | 137 |
Chapter 8 | SIRPH: a rapid, quantitative SNuPE-IP RP HPLC method for simultaneous methylation analysis at multiple CpG sites | 151 |
Chapter 9 | Isolation and sequencing of heteroduplex fragments from DHPLC analysis of somatic, low-frequency mutations | 163 |
Chapter 10 | Analysis of promoter methylation using denaturing high-performance liquid chromatography (DHPLC) | 175 |
Index | 187 |
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Add Genetic variance detection, This book is a how to manual for the scientist and researcher who is using or planning on using DHPLC technology for genetic variance detection and a potential source of inspiration for those exploring the limits of this novel and powerful technology. I, Genetic variance detection to the inventory that you are selling on WonderClubX
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Add Genetic variance detection, This book is a how to manual for the scientist and researcher who is using or planning on using DHPLC technology for genetic variance detection and a potential source of inspiration for those exploring the limits of this novel and powerful technology. I, Genetic variance detection to your collection on WonderClub |