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Tumor Targeting in Cancer Therapy Book

Tumor Targeting in Cancer Therapy
Tumor Targeting in Cancer Therapy, , Tumor Targeting in Cancer Therapy has a rating of 4 stars
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  • Tumor Targeting in Cancer Therapy
  • Written by author Michel Pag
  • Published by Springer-Verlag New York, LLC, February 2002
  • In Tumor Targeting in Cancer Therapy, Dr. Michel Pagé and a panel of authoritative experts from the drug industry, clinics, and academia introduce the principles and techniques of tumor targeting and critically survey their applications from laborato
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Preface
Contributors
1The Current Status of Tumor Targeting: A Review3
2Clinical Applications of Targeted Therapeutics79
3Targeting the CD22 Receptor with RNA Damaging Agents109
4The Development of Liposomes for Enhanced Delivery of Chemotherapeutics to Tumors119
5Overcoming Multiple Drug Resistance with Anti-Pgp Carrier137
6Targeting with Transferrin151
7Synthesis and Evaluation of Paclitaxel Immunoconjugate with Antitumor Activity In Vitro165
8The Use of Drug-Monoclonal Antibody Conjugates for the Treatment of Cancer179
9Targeting Vascular Endothelium with Antibodies199
10Targeting B-Cell Non-Hodgkin's Lymphoma with Monoclonal Antibodies211
11From Bench to Bedside: Development of Rituximab (Rituxan), A Monoclonal Antibody for the Therapy of Non-Hodgkin's Lymphoma225
12Mylotarg: The First Antibody-Targeted Chemotherapy Agent239
13[superscript 188]Rhenium-Labeled Trisuccin-[Delta]Ch2HuCC49 as a Radioimmunotherapy Model in Nude Mice257
14General Approach for Targeting Toxins279
15Antibody-Toxin Conjugates: Chemistry of Coupling and Purification289
16Shiga-Like Toxins as Targeted Anticancer Agents307
17Antibody-Directed Enzyme Prodrug Therapy with Carboxypeptidase G2: Clinical Studies321
18Photodynamic Therapy: Targeting Cancer Cells with Photosensitizer-Bioconjugates329
19Tumor Targeting Using PEG-m-THPC for Photodynamic Therapy in a Rat Ovarian-Cancer Model363
20Targeting Tumors with Magnetic Drugs379
21Internalization of Antibodies391
22Bioconjugation and Biodistribution411
23Principles of Antitumor Targeting of Cytotoxic Drugs431
24Targeting by Antibody or Ligand: Which Is Better?449
Index459


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