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Preface | ||
Contributors | ||
1 | The Current Status of Tumor Targeting: A Review | 3 |
2 | Clinical Applications of Targeted Therapeutics | 79 |
3 | Targeting the CD22 Receptor with RNA Damaging Agents | 109 |
4 | The Development of Liposomes for Enhanced Delivery of Chemotherapeutics to Tumors | 119 |
5 | Overcoming Multiple Drug Resistance with Anti-Pgp Carrier | 137 |
6 | Targeting with Transferrin | 151 |
7 | Synthesis and Evaluation of Paclitaxel Immunoconjugate with Antitumor Activity In Vitro | 165 |
8 | The Use of Drug-Monoclonal Antibody Conjugates for the Treatment of Cancer | 179 |
9 | Targeting Vascular Endothelium with Antibodies | 199 |
10 | Targeting B-Cell Non-Hodgkin's Lymphoma with Monoclonal Antibodies | 211 |
11 | From Bench to Bedside: Development of Rituximab (Rituxan), A Monoclonal Antibody for the Therapy of Non-Hodgkin's Lymphoma | 225 |
12 | Mylotarg: The First Antibody-Targeted Chemotherapy Agent | 239 |
13 | [superscript 188]Rhenium-Labeled Trisuccin-[Delta]Ch2HuCC49 as a Radioimmunotherapy Model in Nude Mice | 257 |
14 | General Approach for Targeting Toxins | 279 |
15 | Antibody-Toxin Conjugates: Chemistry of Coupling and Purification | 289 |
16 | Shiga-Like Toxins as Targeted Anticancer Agents | 307 |
17 | Antibody-Directed Enzyme Prodrug Therapy with Carboxypeptidase G2: Clinical Studies | 321 |
18 | Photodynamic Therapy: Targeting Cancer Cells with Photosensitizer-Bioconjugates | 329 |
19 | Tumor Targeting Using PEG-m-THPC for Photodynamic Therapy in a Rat Ovarian-Cancer Model | 363 |
20 | Targeting Tumors with Magnetic Drugs | 379 |
21 | Internalization of Antibodies | 391 |
22 | Bioconjugation and Biodistribution | 411 |
23 | Principles of Antitumor Targeting of Cytotoxic Drugs | 431 |
24 | Targeting by Antibody or Ligand: Which Is Better? | 449 |
Index | 459 |
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