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Selective Estrogen Receptor Modulators Book

Selective Estrogen Receptor Modulators
Selective Estrogen Receptor Modulators, Experimental and clinical researchers from a wide range of disciplines present a wealth of fresh scientific information on the biochemistry, molecular biology, pharmacology, and clinical activity of SERMs. The basic science chapters of the book focus-with, Selective Estrogen Receptor Modulators has a rating of 4 stars
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Selective Estrogen Receptor Modulators, Experimental and clinical researchers from a wide range of disciplines present a wealth of fresh scientific information on the biochemistry, molecular biology, pharmacology, and clinical activity of SERMs. The basic science chapters of the book focus-with, Selective Estrogen Receptor Modulators
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  • Selective Estrogen Receptor Modulators
  • Written by author Andrea Manni
  • Published by Springer-Verlag New York, LLC, October 2007
  • Experimental and clinical researchers from a wide range of disciplines present a wealth of fresh scientific information on the biochemistry, molecular biology, pharmacology, and clinical activity of SERMs. The basic science chapters of the book focus-with
  • Experimental and clinical researchers from a wide range of disciplines present a wealth of fresh scientific information on the biochemistry, molecular biology, pharmacology, and clinical activity of SERMs. The basic science chapters of the book focus-with
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Authors

Preface
Contributors
IMolecular Mechanisms of Estrogen Receptor Function
1Structure and Function of the Estrogen Receptor3
2Ligand-Induced Conformational Changes in Estrogen Receptors-[alpha] and -[beta]19
3Expression and Function of Estrogen Receptors-[alpha] and -[beta]29
4SERM Modulation of Gene Expression: Role of Coactivators and Corepressors57
5Crosstalk Between Estrogen Receptors and Growth Factor Signaling77
IITissue-Specific Effects of Estrogens and SERMs
6Direct Estrogen Effects on the Cardiovascular System99
7Estrogens and the Brain: Implications for the Treatment of Postmenopausal Women121
IIIPreclinical Studies
8Insights into the Molecular Mechanism of SERMs Through New Laboratory Models147
9Third- and Fourth-Generation SERMs167
IVOrgan Specific Effects of Estrogens and SERMs
10SERMs' Effect on the Neuroendocrine System and the Reproductive Organs191
11Epidemiology of Cardiovascular Disease in Women: Role of Estrogens207
12SERMs Effects on Cardiovascular Risk Factors and Disease223
13Estrogen and the Skeleton237
14Effects of SERMs on Bone in Clinical Studies245
15Estrogens and SERMs: Clinical Aspects of Cognition with Aging and Neurodegenerative Disorders255
VSERMs and Endocrine Dependent Tumors
16SERMs and Breast Cancer Prevention267
17SERMs in Postmenopausal Women's Health279
VIRoles of Estrogens and SERMs in Postmenopausal Hormone Replacement Therapy
18Menopause Therapy: An Individualized Approach299
19Alternatives to Estrogen for Treatment of Menopause313
20Phytoestrogens in the Context of SERMs345
Index365


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