Matrix Metalloproteinase Inhibitors in Cancer Therapy Book

	Preface
	Contributors
1	Biology and Regulation of the Matrix Metalloproteinases	1
2	Substrate Specificity of MMPs	39
3	The Tissue Inhibitors of Metalloproteinases (TIMPs): Biology and Regulation	67
4	Matrix Metalloproteinases in Cancer	85
5	Hydroxamic Acid Matrix Metalloproteinase Inhibitors	113
6	Prinomastat: A Potent and Selective Matrix Metalloprotease Inhibitor - Preclinical and Clinical Development for Oncology	143
7	A Potent Nonpeptidic Matrix Metalloproteinase Inhibitor: Discovery of BAY 12-9566	175
8	D1927 and D2163: Novel Mercaptoamide Inhibitors of Matrix Metalloproteinases	193
9	Research on MMP Inhibitors with Unusual Scaffolds	223
10	Matrix Metalloproteinase Inhibitors: Therapeutic Applications Outside of Oncology	245
	Index	255