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Preface | ||
Contributors | ||
Pt. I | Hormonal Control of Mammary Development and Growth | |
1 | Hormonal Control of Normal Breast Morphology and Function | 3 |
2 | Interactions Between Estradiol and Progesterone in Normal Breast: Implications for Mammary Carcinogenesis | 21 |
3 | Expression and Regulation of Insulin-like Growth Factors and Their Binding Proteins in the Normal Breast | 39 |
Pt. II | Carcinogenesis | |
4 | Estrogens and Breast Cancer: An Epidemiologic Perspective | 55 |
5 | Androgens, Estrogens, and Breast Cancer Risk | 69 |
6 | Local Estrogen Production: Is Aromatase An Oncogene? | 79 |
7 | Oncogenes and Mammary Carcinogenesis | 93 |
8 | Categorization of Breast Cyst Fluid and Breast Cancer Risk | 109 |
Pt. III | Tumor Progression | |
9 | The Role of Tumor Suppressor Genes in Breast Cancer Progression | 119 |
10 | Oncogene Activation and Breast Cancer Progression | 133 |
11 | Interactions Between Stroma and Epithelium in Breast Cancer: Implications for Tumor Genesis, Growth, and Progression | 155 |
12 | The Role of Angiogenesis in the Transition to Hormone Independence and Acquisition of the Metastatic Phenotype | 169 |
13 | Role of the IGF System in Breast Cancer Proliferation and Progression | 187 |
14 | Prognostic and Predictive Factors in Breast Cancer | 205 |
15 | Role of the Polyamine Pathway in the Natural History of Breast Cancer | 221 |
Pt. IV | Estrogen, Progestins, and Prolactin in Breast Cancer Biology: Targets for Treatment | |
16 | Aromatase Inhibitors in Breast Carcinoma | 233 |
17 | Role of Progestins and Progesterone Receptors in Breast Cancer Biology | 245 |
18 | Prolactin and its Receptors in Human Breast Cancer | 261 |
Pt. V | Endocrine Therapy of Breast Cancer | |
19 | Pharmacology and Use of Antiestrogens in Treatment and Chemoprevention of Breast Cancer | 283 |
20 | LHRH Superagonists and Antagonists in the Treatment of Breast Cancer | 313 |
Pt. VI | Benign Breast Disease | |
21 | Benign Breast Lesions: Pathologic Classification and Risk Potential | 331 |
22 | Hormonal Treatment of Fibrocystic Disease | 347 |
23 | Gynecomastia and Galactorrhea | 359 |
Index | 383 |
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