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Foreword | ||
Preface | ||
Contributors | ||
List of Color Plates | ||
Ch. 1 | The IL-2 Deficiency Syndrome: A Lethal Disease Caused by Abnormal Lymphocyte Survival | 1 |
Ch. 2 | IL-7 Knockout Mice and the Generation of Lymphocytes | 21 |
Ch. 3 | Lymphoid Development and Function in IL-7R-Deficient Mice | 37 |
Ch. 4 | CD40 Ligand Knockout Mice | 53 |
Ch. 5 | Physiological, Immunological, and Pathological Functions of Tumor Necrosis Factor (TNF) Revealed by TNF Receptor-Deficient Mice | 69 |
Ch. 6 | Cooperation Between the TNF Receptors Demonstrated by TNF Receptor Knockout Mice | 89 |
Ch. 7 | Immunodeficiency of Tumor Necrosis Factor and Lymphotoxin-[alpha] Double-Deficient Mice | 103 |
Ch. 8 | Characterization of Lymphotoxin-[alpha]-Deficient Mice | 119 |
Ch. 9 | Interleukin-1[beta]-Deficient Mice | 129 |
Ch. 10 | Functional Phenotype of Mice Deficient in the IL-1R Type 1 Gene: A Comparison with Other Genetically Modified Mice | 155 |
Ch. 11 | Mice Deficient in Interleukin-1[beta] Converting Enzyme | 173 |
Ch. 12 | Neutrophilia and B-Cell Plasmacytosis in Mice Lacking the Murine IL-8 Receptor Homolog | 189 |
Ch. 13 | Knockouts of Interferons, Interferon Receptors and Interferon Signaling Components | 207 |
Ch. 14 | IL-6 Gene Knockout Mice | 227 |
Ch. 15 | IL-6 Unique Functions in Inflammation, Bone Metabolism, and B-Cell Neoplasias Revealed by Studies on IL-6 Deficient Mice | 237 |
Ch. 16 | Myocardial, Hematological, and Placental Disorders Caused by Targeted Disruption of gp130, A Common Signal Transducer for IL-6 Family of Cytokines | 259 |
Ch. 17 | NF-IL6 Knockout Mice | 287 |
Ch. 18 | Disruption of the LIF Receptor | 315 |
Ch. 19 | Phenotypes of TGF[beta] Knockout Mice | 335 |
Ch. 20 | The Transforming Growth Factor-[beta]1 Knockout Mouse: The Phenotype and Its Implications for TGF[beta]1 Function | 369 |
Ch. 21 | Granulocyte-Macrophage Colony-Stimulation Factor (GM-CSF)-Deficient Mice | 401 |
Ch. 22 | The In Vivo Role of the Receptors for IL-3, GM-CSF, and IL-5 [actual symbol not reproducible] | 419 |
Ch. 23 | Granulocyte Colony-Stimulating Factor (G-CSF)-Deficient Mice | 435 |
Ch. 24 | Reduction of Platelets and Megakaryocytes in c-mpl-Deficient Mice | 457 |
Index | 467 |
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