Developments and ethical considerations in toxicology Book

	Preface
	The Past, Present and Future of Animals in Toxicology	1
	Ethical and Legal Issues in the Use of Drugs in Biomedical Research	13
	The Toxicological Advantages in Using Humans for Studies with Xenobiotics - The Toxicokinetic Viewpoint	21
	Drug Teratogenesis: Extrapolation of Experimental Results to the Human	35
	Is Regulatory Toxicology Best Designed to Protect Man or His Regulators?	50
	Cell Culture Techniques in Biotransformation Studies	60
	Glutathione S-Transferase Polymorphisms in Relation to Toxicity	69
	Polymorphisms and Expression of Cytochrome P450	86
	Applications of NMR in Biotransformation Studies	94
	Nitrogen Losses - Form, Origin and Impact	110
	The Advantages and Disadvantages of Xenobiotics in Plant Foods and Feeds	129
	The Transformation of Toxic Chemicals by Microbial Processes in the Environment: Beneficial or Hazardous?	144
	Cancer and Environmental Chemicals	158
	Integrated Risk Assessment	170
	Selected Poster Abstracts	183
	Index	193