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Health risk assessment Book

Health risk assessment
Health risk assessment, Health Risk Assessment is a comprehensive reference focusing on dermal absorption, cholinesterase inhibition, adverse reproductive effects, and carcinogenicity. The book features contributions from over 40 top scientists and covers topics such as PBPK mod, Health risk assessment has a rating of 3 stars
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Health risk assessment, Health Risk Assessment is a comprehensive reference focusing on dermal absorption, cholinesterase inhibition, adverse reproductive effects, and carcinogenicity. The book features contributions from over 40 top scientists and covers topics such as PBPK mod, Health risk assessment
3 out of 5 stars based on 2 reviews
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  • Health risk assessment
  • Written by author Rhoda G. M. Wang, James B. Knaak, Howard I. Maibach
  • Published by Boca Raton : CRC Press, c1993., 1/28/1993
  • Health Risk Assessment is a comprehensive reference focusing on dermal absorption, cholinesterase inhibition, adverse reproductive effects, and carcinogenicity. The book features contributions from over 40 top scientists and covers topics such as PBPK mod
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Ch. 1 Physiologically Based Pharmacokinetic Modeling to Predict Tissue Dose and Cholinesterase Inhibition in Workers Exposed to Organophosphorus and Carbamate Pesticides 3
Ch. 2 The Application of Pharmacokinetic Models to Predict Target Dose 31
Ch. 3 Cytochrome P450-Dependent Metabolism of Drugs and Carcinogens in Skin 47
Ch. 4 Percutaneous Absorption 63
Ch. 5 In Vitro Skin Metabolism 75
Ch. 6 Animal Models for Percutaneous Absorption 89
Ch. 7 A Comparative Study of the Kinetics and Bioavailability of Pure and Soil-Absorbed Benzene, Toluene, and m-Xylene after Dermal Exposure 105
Ch. 8 Prediction of Human Percutaneous Absorption with Physicochemical Data 117
Ch. 9 Dermal Absorption of TCDD: Effect of Age 127
Ch. 10 Percutaneous Absorption of Chemicals from Water during Swimming and Bathing 135
Ch. 11 Percutaneous Absorption of Contaminants from Soil 145
Ch. 12 General Overview on Toxicological Responses and Routes of Chemical Exposure 159
Ch. 13 Acute Toxicity Testing by the Dermal Route 167
Ch. 14 Subchronic Dermal Exposure Studies with Industrial Chemicals 201
Ch. 15 The Dose Response of Percutaneous Absorption 217
Ch. 16 Reproductive and Developmental Toxicity Studies by Cutaneous Administration 229
Ch. 17 Dermal Carcinogenicity Studies of Petroleum-Derived Materials 263
Ch. 18 Comparison of Results from Carcinogenicity Tests of Two Halogenated Compounds by Oral, Dermal, and Inhalation Routes 275
Ch. 19 The Objectives and Goals of Dermal Carcinogenicity Testing of Petroleum Liquids 283
Ch. 20 Chemical Carcinogenesis in Skin: Causation, Mechanism, and Role of Oncogenes 291
Ch. 21 Incorporating Biological Information into the Assessment of Cancer Risk to Humans Under Various Exposure Conditions and Issues Related to High Background Tumor Incidence Rates 309
Ch. 22 Phototoxicity of Topical and Systemic Agents 331
Ch. 23 Techniques for Assessing the Health Risks of Dermal Contact with Chemicals in the Environment 343
Ch. 24 Interspecies Extrapolation of Toxicological Data 387
Ch. 25 Human Skin Xenografts to Athymic Rodents as a System to Study Toxins Delivered to or Through the Skin 413
Ch. 26 The Isolated Perfused Porcine Skin Flap 439
Ch. 27 Perspectives on Assessment of Risk From Dermal Exposure to Polycyclic Aromatic Hydrocarbons 455
Ch. 28 The Paradox of Herbicide 2,4-D Epidemiology 471
Ch. 29 A Review of Epidemiologic Studies with Regard to Routes of Exposure to Toxicants 491
Index 511


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Health risk assessment, Health Risk Assessment is a comprehensive reference focusing on dermal absorption, cholinesterase inhibition, adverse reproductive effects, and carcinogenicity. The book features contributions from over 40 top scientists and covers topics such as PBPK mod, Health risk assessment

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Health risk assessment, Health Risk Assessment is a comprehensive reference focusing on dermal absorption, cholinesterase inhibition, adverse reproductive effects, and carcinogenicity. The book features contributions from over 40 top scientists and covers topics such as PBPK mod, Health risk assessment

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Health risk assessment, Health Risk Assessment is a comprehensive reference focusing on dermal absorption, cholinesterase inhibition, adverse reproductive effects, and carcinogenicity. The book features contributions from over 40 top scientists and covers topics such as PBPK mod, Health risk assessment

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