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Preface xi
Editors xiii
Contributors xv
Introduction
Epidemiology of Obesity Giovanna Turconi Hellas Cena 3
Epidemiology of Obesity: A Global Burden for the New Millennium Gopal C. Pain 21
Pathophysiology of Obesity
Environmental Estrogens, Endocrine Disruption, and Obesity Frederick S. vom Saal James R. Kirkpatrick Benjamin L. Coe 33
Cigarette Smoking, Inflammation, and Obesity Saibal K. Biswas Ian L. Megson Catherine A. Shaw Irfan Rahman 43
Disordered Eating as a Correlate in the Development of Obesity Gwendolyn W. Pla 63
Role of Neurotransmitters in Obesity Regulation Sunny E. Ohia Catherine A. Opere 71
Neurobiology of Obesity Nina Eikelis 81
Leptin as a Vasoactive Adipokine: Link Between Metabolism and Vasculature Anne Bouloumie Cyrile Anne Curat Alexandra Miranville Karine Lolmede Coralie Sengenes 93
Overview of Ghrelin, Appetite, and Energy Balance Rafael Fernandez-Fernandez Manuel Tena-Sempere 105
Molecular Genetics of Obesity Syndrome: Role of DNAMethylation Rama S. Dwivedi Atul Sahai Bernard L. Mirkin 115
Obesity and Degenerative Diseases
Oxidative Stress Status in Humans with Metabolic Syndrome Chung-Yen Chen Jeffrey B. Blumberg 123
Obesity and Type 2 Diabetes Subhashini Yaturu Sushil K. Jain 139
Angiogenesis-Targeted Redox-Based Therapeutics Shampa Chatterjee Debasis Bagchi Manashi Bagchi Chandan K. Sen 155
Obesity as an Occult Risk Factor for Drug and Chemical Toxicities George B. Corcoran 165
Novel Concept in Obesity Drug Development
Adipose Drug Targets for Obesity Treatment Olivier Boss Lorenz Lehr Jean-Paul Giacobino 177
Safety of Obesity Drugs
Safety of Obesity Drugs Alok K. Gupta Frank L. Greenway 199
Natural, Nutritional, and Physical Approaches to Weight Management
The Fundamental Role of Physical Activity and Exercise in Weight Management Dawn Blatt Cheri L. Gostic 219
Nutritional and Dietary Approaches for Weight Management: An Overview Sanjiv Agarwal 233
Gender Differences in Body Fat Utilization during Weight Gain, Loss, or Maintenance Gabriel Keith Harris David J. Baer 239
Appetite, Body Weight, Health Implications of a Low-Glycemic-Load Diet Stacey J. Bell Wendy Van Ausdal Greg Grochoski 245
Beyond Obesity Prevention: The Anti-Aging Effects of Caloric Restriction Kurt W. Saupe Jacob D. Mulligan 265
Dietary Supplement Carbohydrate Digestion Inhibitors: A Review of the Literature Jay Udani Mary Hardy Ben Kavoussi 279
Vegetarian Diets in the Prevention and Treatment of Obesity Kathryn T. Knecht Hien T. Bui Don K. Tran Joan Sabate 299
The Atkins Paradigm Ariel Robarge Bernard W. Downs 315
Polyphenols from Fruits and Vegetables in Weight Management and Obesity Control Dilip Ghosh Margot A. Skinner 321
Chromium (III) in Promoting Weight Loss and Lean Body Mass Manashi Bagchi Harry G. Preuss Shirley Zafra-Stone Debasis Bagchi 339
An Overview on (-)-Hydroxycitric Acid in Obesity Regulation Shirley Zafra-Stone Manashi Bagchi Harry G. Preuss Gary J. Grover Debasis Bagchi 349
A Review of the Safety and Efficacy of Citrus aurantium in Weight Management Sidney J. Stohs Michael Shara 371
Conjugated Linoleic Acid and Weight Control: From the Biomedical Immune Viewpoint Zwe-Ling Kong 383
The Role of Tea in Weight Management Chithan Kandaswami 401
Laboratory and Clinical Studies of Chitosan Harry G. Preuss Debasis Bagchi Gilbert R. Kaats 413
Phaseolus vulgaris and [alpha]-Amylase Inhibition Dennis E. Meiss 423
Glucomannan in Weight Loss: A Review of the Evidence Barbara Swanson Joyce K. Keithley 433
Role of Caralluma fimbriata in Weight Management Ramasamy V. Venkatesh Ramaswamy Rajendran 443
Role of Medium-Chain Triglycerides ia Weight Management Mary G. Enig 451
Anti-Obesity by Marine Lipids Kazuo Miyashita 463
Dairy Foods, Calcium, and Weight Management Michael B. Zemel 477
Lessons from the Use of Ephedra Products as Dietary Supplements Madhusudan G. Soni Kantha Shelke Rakesh Amin 495
Dietary Supplementation in Weight Loss: A Dietitian's Perspective Betty Wedman-St. Louis 507
Child Obesity and Prevention
Treatment and Prevention of Childhood Obesity and Associated Metabolic Diseases Michael I. Goran Jaimie N. Davies Louise A. Kelly 515
Bariatric Surgery in Weight Management
Bariatric Surgery in Obesity and Reversal of Metabolic Disorders Melania Manco 531
Index 545
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