Animal Models in Orthopaedic Research Book

Pt. I	General Considerations of using Laboratory Animals
1	Ethics and Regulations for the Care and Use of Laboratory Animals	3
2	Experimental Design, Evaluation Methods, Data Analysis, Publication, and Research Ethics	15
3	Animal Selections in Orthopaedic Research	39
4	Surgical Facilities, Peri-operative Care, Anesthesia, and Surgical Techniques	59
5	Euthanasia and Necropsy	71
Pt. II	Evaluation Methods in Orthopaedic Animal Research
6	Methods of Evaluation in Orthopaedic Animal Research	85
7	Histological Study in Orthopaedic Animal Research	115
8	Mechanical Properties and Testing Methods of Bone	139
9	Mechanical Testing of Cartilage	165
10	Mechanical Testing of Ligaments and Tendons	175
Pt. III	Animal Models of Bone Conditions
11	Animal Models of Fracture or Osteotomy	197
12	Animal Models for Testing Bioabsorbable Materials	219
13	Animal Models of Bone Defect Repair	241
14	Animal Models of Osteonecrosis	261
15	Animal Models of Osteopenia or Osteoporosis	279
Pt. IV	Animal Models of Articular Cartilage and Joint Conditions
16	Animal Models of Articular Cartilage Defect	309
17	Animal Models of Meniscal Repair	327
18	Animal Models of Osteoarthritis	349
19	Animal Models of Rheumatoid Arthritis	369
Pt. V	Animal Models of Joint Replacement and Related Conditions
20	Animal Models for Studying Soft Tissue Biocompatibility of Biomaterials	393
21	Animal Models for Studying Bone Ingrowth and Joint Replacement	407
22	Animal Models for Investigations of Biomaterial Debris	427
23	Animal Models of Orthopaedic Prosthetic Infection	443
Pt. VI	Animal Models for the Study of Ligaments and Tendons
24	Animal Models of Ligament Repair	461
25	Animal Models of Tendon Repair	477
26	Animal Models for Ligament and Tendon Fixation	491
Pt. VII	Animal Models of Spinal Conditions
27	Animal Models of Spinal Instability and Spinal Fusion	505
28	Animal Models of Spinal Cord Compression	527
29	Animal Models for Reconstruction of Vertebral Column and Intervertebral Disc	539
30	Animal Models of Scoliosis	549
Pt. VIII	Microsurgical Technique
31	Use of Microsurgical Technique in Orthopaedic Animal Models	567
	App. 1: Abbreviations	583
App. 2	Journals and Publications Related to Orthopaedic Research and Laboratory Animals	585
App. 3	Major Sources of Laboratory Animals	587
	Index	589