Molecular biology of cardiovascular disease Book

Overview of Methodology and Introduction to Techniques

DNA and RNA, Loewe O. Go Cloning and Expression, Andrew R. Marks Expression Cloning and Screening for Unknown Genes, Mark E. Lieb Gene Transfer into Adult Cardiac Myocytes in Vivo by Direct Injection of DNA, Koji Hasegawa and Richard N. Kitsis Studies of Cardiac Myocytes in Culture: A Developmental Perspective, D. Stave Kohtz Congenital Heart Disease: Gene Defects and Molecular Biological Studies, Bruce D. Gelb

Transmembrane Signaling

Molecular Biology of Nitric Oxide Synthases, Thomas Michel, Santiago Lamas, and Kazuhiro Sase Signaling Through Heterotrimeric G Proteins, Yibang Chen, Anya Harry, and Ravi Iyengar Molecular Physiology of Cardiac Sodium Channels, Sarah K. England and Michael M. Tamkun Molecular Properties of Cardiac Potassium Channels in Health and Disease, Marie-Noelle S. Langan and Diomedes E. Logothetis Plasma membrane Calcium Channels, Andrew R. Marks Structure and Function of Calcium Release Channels, Andrew R. Marks Advances in the Molecular Characterization of the Na+/Ca2+ Exchanger, Dan H. Schulze and W. J. Lederer

Signaling in Disease States

Tyrosine Kinases in the Regulation of Vascular Smooth Muscle Function, Marshall A. Corson and Bradford C. Berk Myocardial Growth Factors, W. Robb MacLellan, James Hawker, and Michael D. Schneider Gene Therapy and the Vessel Wall, Jonathan D. Marmur The Extracellular Matrix and Smooth Muscle Cell Migration, Andrea S. Weintraub and Mark B. Taubman Microfibril Pathology and Cardiovascular Manifestations in Marfan Syndrome, Lygia V. Pereira, Hui Zhang, and Francesco Ramirez The Role of Tissue Factor in Arterial Thrombosis and Atherosclerosis, Mark B. Taubman Regulation of the Production of Lipoproteins Containing Apolipoprotein B, Edward A. Fisher Platelets and Cardiovascular Disease, Christine M. Grimaldi and Deborah L. French

Glossary

Appendix: Genetic Cardiovascular Disease