Purines and Myocardial Protection Book

1	Physiologic and Pathophysiologic Significance of Purine Metabolism in the Heart	3
2	Purine Metabolism in the Ischemic Canine and Human Immature Myocardium Deficient of 5'-Nucleotidase	17
3	Cardiac Adenosine Metabolism: Physiological Implications	39
4	Purines Metabolism in Human Cardiomyocytes and Endothelium-Implications for Protection of the Heart during Cardiac Surgery	55
5	Assessment of Interstitial Fluid Adenosine: Implications for Exogenous or Endogenous and Endogenous Adenosine-Mediated Cardioprotection	81
6	Adenosine and Coronary Vascular Pharmacology	95
7	Alternations in Energy Substrate Metabolism during Oxidative Stress	105
8	Purines and Myocardial Protection: An Overview	119
9	Nucleoside Transport Protein: Properties and Regulation	151
10	Role of Nucleoside Transport in Myocardial Injury and Protection: Separation Between Ischemic and Reperfusion Injury using a Selective Nucleoside Transport Blocker, p-Nitrobenzylthoinosine NBMPR	165
11	Myocardial Protection using Nucleoside Transport Inhibitors	183
12	Selective Blockade of Nucleoside Transport by NBMPR Attenuates Reperfusion-Mediated Ventricular Arrhythmias	197
13	Nucleoside Transport in the Human Myocardium	209
14	Selective Nucleoside Transport Blocker NBMPR Attenuates Myocardial Stunning in a Rabbit Model Deficient of Xanthine Oxidase	219
15	Amplification of Endogenous Adenosine by "Adenosine Regulating Agents" as a Therapeutic Approach to the Treatment of Cardiac Ischemic Syndromes	231
16	Organ Protection with ATP-Magnesium Chloride	261
17	Adenosine and Adenosine Receptor Protection of the Ischemic Heart	285
18	Effect of Adenosine on Myocardial Stunning	297
19	Cardioprotection from Ischemic-Reperfusion Injury by Adenosine	315
20	Cardioprotection with Adenosine, Inosine and Hypoxanthine	345
21	Adenosine and Adrenergic Mediated Effects in the Heart	359
22	Effects of Adenosine on Ventricular Tachycardia	373
23	Purines and Ventricular Arrhythmias	383
24	Adenosine and the Polymorphonuclear Leukocyte Function Mechanisms and Production	395
25	Purines and Regulation of Platelet Activation	409
26	Myocardial Preconditioning: From a Model to a Phenomenon	421
27	ATP Metabolism and Ischemic Preconditioning	433
28	Do Adenosine A[subscript]3 Receptors Cause Preconditioning?	447
29	K[subscript ATP] Channels and Adenosine Receptors and Ischemic Preconditioning	459
30	Role of Activation of Ecto-5'-Nucleotidase for Cardioprotection in Ischemic and Reperfusion Injury: Role of Purine and Adenosine Metabolism	469
31	Ischemic Preconditions in a Model of Isolated Cardiomyocytes	481
32	Integration of Adenosine and Noradrenergic Pathways in Cardiac Preconditioning	499
33	Myocardial Stunning and Preconditioning during Non-cardioplegic Warm Intermittent Aortic Cross-clamping	513
34	Energy and Cation Control in the Reoxygenated Myocardial Cell	527
35	Cystolic Calcium Transport during Myocardial Protection	537
36	Future Therapeutic Use of Purines in Myocardial Protection	553
	Index	563