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Book Categories |
Foreword | ||
Preface | ||
Ch. 1 | Introduction and background | 1 |
Ch. 2 | Molecular diagnostic techniques in breast cancer | 12 |
Ch. 3 | Clinical and molecular epidemiology of breast cancer | 34 |
Ch. 4 | Predisposition for breast cancer | 48 |
Ch. 5 | Screening and early detection, serum and nipple aspirates, routine and molecular methods including reverse transcriptase-polymerase chain reaction, and proteomics | 60 |
Ch. 6 | Genomic and molecular classification of breast cancer | 81 |
Ch. 7 | Cytology : clinical sample procurement and on-slide technologies | 96 |
Ch. 8 | Histopathology of breast cancer : correlation with molecular markers | 106 |
Ch. 9 | Sentinel lymph node dissection and micrometastasis detection in bone marrow and lymph nodes | 117 |
Ch. 10 | Prognostic and predictive factors overview | 128 |
Ch. 11 | Breast cancer cytogenetics, chromosomal abnormalities, and comparative genomic hybridization | 142 |
Ch. 12 | DNA ploidy and S phase analysis in breast cancer | 153 |
Ch. 13 | Cell proliferation markers and cell cycle regulators in breast cancer | 169 |
Ch. 14 | Targeted therapy for cancer : integrating diagnostics and therapeutics | 192 |
Ch. 15 | Hormone receptors and hormonal-based therapy for breast cancer | 207 |
Ch. 16 | HER-2/neu gene and protein in breast cancer | 232 |
Ch. 17 | Epidermal growth factor receptor and other growth factors and receptors | 256 |
Ch. 18 | Tumor-associated proteolytic factors : markers for tumor invasion and metastasis | 276 |
Ch. 19 | Breast cancer and angiogenesis | 289 |
Ch. 20 | Cell adhesion markers | 313 |
Ch. 21 | Programmed cell death and breast cancer | 322 |
Ch. 22 | Oncogenes | 348 |
Ch. 23 | P53 and tumor suppressor genes in breast cancer | 358 |
Ch. 24 | The ubiquitin-proteasome pathway and breast cancer | 373 |
Ch. 25 | DNA repair and the maintenance of genomic stability in breast cancer | 394 |
Ch. 26 | Biologic and clinical significance of DNA gene methylation and epigenetic events in breast cancer | 411 |
Ch. 27 | DNA methylation in breast cancer as diagnostic markers and targets for cancer therapy | 422 |
Ch. 28 | Pharmacogenetics, pharmacogenomics, and predicting response to therapy | 439 |
Ch. 29 | Mammography and molecular imaging | 457 |
Ch. 30 | Translation of molecular markers to clinical practice | 469 |
Ch. 31 | Regulatory aspects and implications of molecular testing in the United States | 478 |
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