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Bone Marrow Disorders : The Biological Basis of Treatment Book

Bone Marrow Disorders : The Biological Basis of Treatment
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Bone Marrow Disorders : The Biological Basis of Treatment, The last decade has seen major advances in the understanding of the function of the bone marrow and the factors which regulate the formation of blood and the immune function. Technological advances have allowed both a more thorough examination of the proc, Bone Marrow Disorders : The Biological Basis of Treatment
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  • Bone Marrow Disorders : The Biological Basis of Treatment
  • Written by author A. J. Barrett, M. Y. Gordon
  • Published by Wiley-Blackwell, 1993/03/18
  • The last decade has seen major advances in the understanding of the function of the bone marrow and the factors which regulate the formation of blood and the immune function. Technological advances have allowed both a more thorough examination of the proc
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Book Categories

Authors

Foreword
Preface to the Second Edition
Preface to the First Edition
1 Advances in Experimental Haematology 1
Measurement of haemopoietic stem cells 4
Molecular biology of growth factors and their receptors 10
Biological effects of growth factor - target cell interactions 43
2 Treatment Strategies in Bone Marrow Disorders 73
Haematological malignancies 73
Congenital bone marrow disorders 112
Aplastic anaemia and drug-induced cytopenias 122
3 Molecular Pathology of Haematological Disorders 141
Methods 143
Genes and proteins of special interest 152
Applications to haematological disease 156
4 Bone Marrow Transplantation 190
Historical introduction 190
Current results of BMT 194
Animal models of BMT 195
Stem cells and engraftment 200
Recovery of haemopoiesis after BMT 204
Immune recovery 208
Tissue typing and matching 211
Clinical outcome and its relationship to the source of stem cells used for transplantation 224
Cure of leukaemia by allogeneic BMT 225
Cure of haematological malignancies by ABMT 233
Cure of non-malignant disorders by BMT 238
GVHD 242
Pathophysiology of acute GVHD 245
Prevention and treatment of GVHD 248
Graft failure 253
Infections after BMT 258
Non-haematological complications after BMT 266
5 Clinical Application of Haemopoietic Growth Factors 281
Experimental background 288
Principles and practice of HGF therapy 292
Clinical HGF therapy 296
6 Immunotherapy 324
Historical introduction 324
Tumour immunobiology 326
Immunotherapy 355
Index 405


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Bone Marrow Disorders : The Biological Basis of Treatment, The last decade has seen major advances in the understanding of the function of the bone marrow and the factors which regulate the formation of blood and the immune function. Technological advances have allowed both a more thorough examination of the proc, Bone Marrow Disorders : The Biological Basis of Treatment

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Bone Marrow Disorders : The Biological Basis of Treatment, The last decade has seen major advances in the understanding of the function of the bone marrow and the factors which regulate the formation of blood and the immune function. Technological advances have allowed both a more thorough examination of the proc, Bone Marrow Disorders : The Biological Basis of Treatment

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Bone Marrow Disorders : The Biological Basis of Treatment, The last decade has seen major advances in the understanding of the function of the bone marrow and the factors which regulate the formation of blood and the immune function. Technological advances have allowed both a more thorough examination of the proc, Bone Marrow Disorders : The Biological Basis of Treatment

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