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List of contributors ix
Acknowledgments xi
Introduction xiii
1 Study design and protocol development process T. Scott Stroup Joseph P. McEvoy Jeffrey A. Lieberman 1
2 Statistical considerations Sonia M. Davis Gary G. Koch Robert A. Rosenheck Vicki G. Davis 22
3 Effectiveness and efficacy: staying on treatment and symptom reduction Joseph P. McEvoy T. Scott Stroup Jeffrey A. Lieberman 39
4 Cost-effectiveness and cost-benefit analysis Robert A. Rosenheck Douglas L. Leslie 57
5 Psychosocial functioning in patients with chronic schizophrenia: findings from the NIMH CATIE study Marvin S. Swartz 80
6 Neurocognition Richard S. E. Keefe 97
7 Vocational outcomes Sandra G. Resnick Robert A. Rosenheck 120
8 Family outcomes Deborah A. Perlick Richard Kaczynski Robert A. Rosenheck 133
9 Extrapyramidal side effects Stanley N. Caroff Del D. Miller Robert A. Rosenheck 156
10 Metabolic side effects and risk of cardiovascular disease Jonathan M. Meyer Donald C. Goff Joseph P. McEvoy 173
11 Substance use in persons with schizophrenia: incidence, baseline correlates, and effects on outcome Fred Reimherr Marvin S. Swartz John L. Olsen 189
12 Violence in schizophrenia: prevalence, correlates, and treatment effectiveness Jeffrey Swanson Richard Van Dorn 207
13 Genetic investigations in the Catie sample James J. Crowley Patrick F. Sullivan 237
14 Human subjects considerations T. Scott Stroup Paul Appelbaum 255
15 Population pharmacokinetics of antipsychotics Kristin L. Bigos Robert R. Bies Stephen R. Marder Bruce G. Pollock 267
16 Implications for research design and study implementation T. Scott Stroup Jeffrey A. Lieberman 281
17 Conclusion and implications for practice and policy Robert A. Rosenheck T. Scott Stroup Jeffrey A. Lieberman 288
Index 307
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Uys Marietjie
reviewed Antipsychotic Trials in Schizophrenia: The CATIE Project on March 11, 2012
Antipsychotic Trials in Schizophrenia
Very well-researched and thorough review of different health policies. The author is clearly very knowledgeable; I just don't like his writing style. Come on, guy, I trust that you're smart and qualified, I don't need you impress me with your long-ass sentences and 50,000 different ways of saying "reform". Examples he gives are also quite jumpy, and references Germany, US, Netherlands, and Singapore a whole lot.
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Add Antipsychotic Trials in Schizophrenia: The CATIE Project, Antipsychotic medications are a key treatment for schizophrenia and sales of antipsychotic drugs approach $20 billion per year, with fierce marketing between the makers of the drugs. The U.S. National Institute of Mental Health sponsored the Clinical Anti, Antipsychotic Trials in Schizophrenia: The CATIE Project to the inventory that you are selling on WonderClubX
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