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Stereoselective Synthesis Book

Stereoselective Synthesis
Stereoselective Synthesis, Introduces a new, simplified classification for stereoselective reactions based on changes in the number of chiral centres taking place, emphasizing the three-dimensional representations of transition states in which stereoselectivity is determined. Using, Stereoselective Synthesis has a rating of 3 stars
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Stereoselective Synthesis, Introduces a new, simplified classification for stereoselective reactions based on changes in the number of chiral centres taking place, emphasizing the three-dimensional representations of transition states in which stereoselectivity is determined. Using, Stereoselective Synthesis
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  • Stereoselective Synthesis
  • Written by author Robert S. Atkinson
  • Published by Wiley, John & Sons, Incorporated, August 1995
  • Introduces a new, simplified classification for stereoselective reactions based on changes in the number of chiral centres taking place, emphasizing the three-dimensional representations of transition states in which stereoselectivity is determined. Using
  • Stereoselective Synthesis considers the methods available for the synthesis of simple target molecules, the majority containing not more than two chiral centres, as single stereoisomers. This volume focuses on the factors which give rise to the stereosele
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Introduction
Abbreviations
1Selectivity in organic synthesis: stereochemical vocabulary1
2Classification of stereochemical reactions used in this book37
3Type 0 reactions: reactions in which no new chiral centres are created49
4Type I reactions: those proceeding with either inversion or with retention of configuration at a single chiral centre79
5Simple chirality transfer reactions: those in which a single chiral centre is transferred with concomitant migration of one or more double bonds109
6Type II reactions: simple diastereoselectivity in 1,2-additions to alkenes, Diels-Alder and 1,3-dipolar cycloadditions and the ene reaction147
7Type II reactions: occasional diastereoselectivity191
8Type II reactions: simple diastereoselectivity in the aldol and related reactions217
9Type III reactions: those involving asymmetric induction243
10Substrate-controlled diastereoselective reactions (Type III[subscript s.c.]) mediated by stereoelectronic effects: torsional strain and [sigma]-[pi] interactions273
11Substrate-controlled diastereoselective reactions (Type III[subscript s.c.]) mediated by ring formation315
12Type III reagent-controlled reactions (Type III[subscript r.c.])359
13Type II/III reactions and those involving chirality transfer381
14Catalytic enantioselective reactions (Type III[subscript cat. enant.])419
15Type III[subscript s.c./r.c.] reactions (Double asymmetric induction)473
16Type III reactions of diastereotopic and enantiotopic atoms and groups; enzyme catalysed reactions489
Index523


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