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Contributors vii
Preface ix
Development of Vaccine Adjuvants: A Historical Perspective Gary Ott Gary Van Nest 1
Antigen Processing and Presentation Subash Sad 33
Mechanisms of Adjuvant Action Nils Lycke 53
Aluminum-Containing Adjuvants: Properties, Formulation, and Use Stanley L. Hem Harm HogenEsch 81
MF59: A Safe and Potent Oil-in-Water Emulsion Adjuvant Derek T. O'Hagan Manmohan Singh 115
TLR4 Agonists as Vaccine Adjuvants David A. Johnson Jory R. Baldridge 131
Immunostimulatory CpG Oligodeoxynucleotides as Vaccine Adjuvants Dennis M. Klinman Debbie Currie Hidekazu Shirota 157
Small Molecule Immunopotentiators as Vaccine Adjuvants Fengfeng Xu Nicholas M. Valiante Jeffrey B. Ulmer 175
New ISCOMs Meet Unsettled Vaccine Demands Bror Morein Kefei Hu Karin Lovgren Erik D'Hondt 191
Surface-Charged Poly(lactide-co-glycolide) Microparticles as Novel Antigen Delivery Systems Manmohan Singh James Chesko Jina Kazzaz Mildred Ugozolli Padma Malyala Derek T. O'Hagan 223
Liposomal Cytokines and Liposomes Targeted to Co-Stimulatory Molecules as Adjuvants for HIV Subunit Vaccines Bulent Ozpolat Lawrence B. Lachman 249
Archaeosome Vaccine Adjuvants for Cross-Priming CD8[superscript +] T-Cell Immunity Lakshmi Krishnan G. Dennis Sprott 263
Mucosal Adjuvants and Delivery Systems Michael Vajdy 295
Cytokines as Vaccine Adjuvants Nejat K. Egilmez 327
Polyphosphazenes as Vaccine Adjuvants Alexander K. Andrianov 355
Vaccine Delivery by Transdermal Electroporation Amit Misra 379
Nonclinical Safety Assessment of Vaccines and the Evaluation of Novel Adjuvants and Delivery Systems Jose A. Lebron Jayanthi J. Wolf Catherine V. Kaplanski Brian J. Ledwith 403
Safety Evaluation of Vaccine Adjuvants Erik B. Lindblad 421
Index 445
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Add Vaccine Adjuvants and Delivery Systems, The authoritative reference on recent developments in vaccinology New technologies, including recombinant protein and DNA, have sparked phenomenal progress in vaccine development and delivery systems. This unique resource brings scientists up to date o, Vaccine Adjuvants and Delivery Systems to your collection on WonderClub |