Chemometric Methods in Capillary Electrophoresis Book

Preface ix

Acknowledgments xi

Editor Biographies xii

Contributors xv

Key acronyms xix

I Experimental Design And Optimization Considerations 1

1 Introduction Grady Hanrahan Frank A. Gomez 3

2 Experimental Design In Method Optimization And Robustness Testing Bieke Dejaegher Alexandra Durand Yvan Vander Heyden 11

3 Chemometrical Experimental Design-based Optimization Studies In Capillary Electrophoresis Applications Ruthy Montes Toni Ann Riveros Froseen Dahdouh Grady Hanrahan Frank A. Gomez 75

4 Application Of Chemometric Methods In Drug Purity Determination By Capillary Electrophoresis Gerhard K.E. Scriba 93

5 Optimization Of Micellar Electrokinetic Chromatography Separation Conditions By Chemometric Methods Jessica L. Felhofer Carlos D. Garcia 113

6 Chemometric Methods For The Optimization Of Ce And Ce-Ms In Pharmaceutical, Environmental, And Food Analysis Javier Hernández-Borges Miguel Ángel Rodriguez-Delgado Alejandro Cifuentes 133

7 Optimization Of The Separation Of Amino Acids By Capillary Electrophoresis Using Artificial Neural Networks Amanda Van Gramberg Alison Beavis Lucas Blanes Philip Doble 169

II Exploratory Data Analysis, Prediction, And Classification 181

8 Development Of Capillary Electrophoresis Fingerprints And Multivariate Statistics For The Differentiation Of Opium And Poppy Straw Samples Raymond G. Reid Susanne P. Boyle Ann S. Low David G. Durham 183

9 Multivariate Curve Resolution Based On Alternating Least Squares In Capillary Electrophoresis Javier Saurina 199

10 Application Of Chemometrics In Capillary Electrophoresis Analysis Of Herbal Medicines Shao-Ping Li Xiao-Jia Chen Feng-Qing Yang 227

11 Clinical PatternRecognition Analysis Applying Artificial Neural Networks Based On Principal Component Analysis Input Selection Yaxiong Zhang Hua Li 243

12 Chemometric Methods Applied To Genetic Analyses By Capillary Electrophoresis And Electrophoresis Microchip Technologies Maribel Elizabeth Funes-Huacca Juliana Vieira Alberice Lucas Blanes Emanuel Carrilho 261

13 Exploratory Data Analysis And Classification Of Capillary Electrophoretic Data Melanie Dumarey Bieke Dejaegher Alexandra Durand Yvan Vander Heyden 291

III Quantitative Structure Relationships 323

14 Chemometrical Modeling Of Electrophoretic Mobilities In Capillary Electrophoresis Mehdi Jalali-Heravi 325

15 Assessment Of Solute-Micelle Interactions In Electrokinetic Chromatography Using Quantitative Structure-Retention Relationships Edgar P. Moraes Fernando G. Tonin Luís G. Dias Jo&atild;o P.S. Farah Marina P.M. Tavares 345

16 Chemometrical Analysis Of Cheese Proteolysis Profiles By Capillary Electrophoresis: Prediction Of Ripening Times Natividad Ortega Silvia M. Albillos Maria D. Busto 367

IV Transformation Techniques 389

17 Transformation Techniques For Capillary And Microchip Electrophoresis Takashi Kaneta 391

Index 407