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Preface to Series vii
Introduction ix
Contributors xi
1 Theoretical Modeling of Radiation-Induced DNA Damage Anil Kumar Michael D. Sevilla 1
2 Radical Reaction Pathways Initiated by Direct Energy Deposition in DNA by Ionizing Radiation William A. Bernhard 41
3 Chemical Reactions of the Radical Cations of Nucleobases in Isolated and Cellular DNA. Formation of Single-Base Lesions Jean Cadet Thierry Douki Didier Gasparutto Jean-Luc Ravanat J. Richard Wagner 69
4 Reactivity of Nucleic Acid Sugar Radicals Chryssostomos Chatgilialoglu 99
5 Pyrimidine Nucleobase Radical Reactivity Marc M. Greenberg 135
6 Reactivity of 5-Halopyrimidines in Nucleic Acids Ryu Tashiro Hiroshi Sugiyama 163
7 Kinetics of Long-Range Oxidative Electron Transfer through DNA Kiyohiko Kawai Tetsuro Majima 191
8 Radical Intermediates during Reductive Electron Transfer through DNA Reji Varghese Hans-Achim Wagenknecht 211
9 Low-Energy Electron Interaction with DNA: Bond Dissociation and Formation of Transient Anions, Radicals, and Radical Anions Lion Sanche 239
10 Electronic-Affinic Radio sensitizers Peter Wardman 295
11 Reactions of Reactive Nitrogen Species and Carbonate Radical Anions with DNA Vladimir Shafirovich Conor Crean Nicholas E. Geacintov 325
12 Principles and Applications of Electrochemical Oxidation of Nucleic Acids H. Holden Thorp Julie M. Sullivan 357
13 DNA Damage Due to Diradical-Generating Cyclizations Sean M. Kerwin 389
14 DNA Damage by Phenoxyl Radicals Richard A. Manderville 421
Index 445
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