Cancer Vaccines and Tumor Immunity Book

Contributors     ix
Foreword: Cancer Vaccines and Cancer Immunotherapy: A New Paradigm   Jeffrey Schlom     xiii
Introduction
Cancer Vaccines: Progress and Promise   Rimas J. Orentas   Bryon Johnson   James Hodge     3
Adjuvant Therapy: Enhancing the Endogenous Immune Response
Fully Synthetic Carboyhydrate-Based Antitumor Vaccines   Rebecca M. Wilson   Samuel J. Danishefsky     15
Bacillus Calmette-Guerin Immunotherapy of Genitourinary Cancer   Donald L. Lamm     29
Stimulation of Toll-Like Receptor 9 for Enhancing Vaccination   Daniel E. Speiser   Arthur M. Krieg     43
Antigen-Specific Therapy: Novel Presentation of Peptide and Protein Antigens
Polyepitope Vaccines   Corey Smith   Rajiv Khanna     69
Antigen-Specific Cancer Immunotherapy: HPV-Associated Cervical Cancer as a Model System   Shaw-Wei D. Tsen   Chien-Fu Hung   T.-C. Wu     79
Poxviral Vectors for Cancer Vaccines: State of the Art   Elizabeth K. Wansley     95
Immunotherapeutic Strategies Against Cancer Using Listeria monocytogenes as a Vector for Tumor Antigens   Nicholas C. Souders   Thorsten Verch   Yvonne Paterson     113
Coupling Innate and Adaptive Immunity with Yeast-BasedCancer Immunotherapy   Sibyl Munson   Joanne Parker   Thomas H. King   Yingnian Lu   Victoria Kelley   Zhimin Guo   Virginia Borges   Alex Franzusoff     131
Cell-Based Therapy: Using Cancer Cells as a Means to Induce Specific Tumor Immunity
Allogeneic Whole-Cell Vaccines   John Copier   Angus Dalgleish     153
Jump-Starting Tumor Immunity with Breast Cancer Therapeutics   Leisha A. Emens     169
T-Regulatory Cell Manipulation in Tumor Immunotherapy   Jens Ruter   Brian G. Barnett   Ilona Kryczek   Michael J. Brumlik   Benjamin J. Daniel   George Coukos   Weiping Zou   Tyler J. Curiel     189
Tumor Vaccination After Autologous HSCT: What Has Been Learned from Experimental Models   Weiqing Jing   Bryon D. Johnson     205
Vaccines in the Setting of Hematopoietic Stem Cell Transplantation   Ronald Gress   Claude Sportes     217
Intratumor Generation of Vigorous Antitumor Immune Responses   Ping Yu   Yang-Xin Fu     229
Cancer Immunotherapy: Untapping the Potential of Costimulatory Molecules Beyond CTLA-4   Mathew Augustine   Lieping Chen     243
Defining Effective Clinical Responses
Advances in Immune Monitoring Strategies for Cancer Vaccines and Immunotherapy   Seunghee Kim-Schulze   Moshe Ornstein   Howard L. Kaufman     271
Immune Evaluation of Cancer Vaccines   Theresa L. Whiteside     291
Index     309