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1 The components and foundations of signalling 1
2 Enzymes and receptors - quantitative aspects 39
3 Modules and motifs in transduction 71
4 Protein kinase enzymes - activation and auto-inhibition 101
5 7-pass receptors and the catabolic response 133
6 Single pass growth factor receptors 179
7 G proteins (I) - monomeric G proteins 215
8 G proteins (II) - heterotrimeric G proteins 245
9 The insulin receptor and the anabolic response 271
10 Mitogens and cell cycle progression 297
App. 1 Worked examples 355
App. 2 RasMol: installation and use 365
Index 377
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