Brain Activation and CBF Control: Proceedings of the Satellite Meeting on Brain Activation and Cerebral Blood Flow Control, Tokyo, Japan, 5-8 June 2001, ICS 1235 Book

	Preface
	List of Active Participants
	Microcirculation - historical background and conceptual update	3
	The circulatory and metabolic correlates of functional activity	15
	Coupling between CBF and CMRO[subscript 2] during neuronal activity	23
	Flow-metabolism regulation during brain activation and respiratory manipulations	33
	Spatial specificity of CBF and BOLD responses induced by neural activity	39
	Activated areas found by BOLD, CBF, CBV and changes in CMRO[subscript 2] during somatosensory stimulation do not co-localize in rat cortex	49
	Quantitative fMRI of rat brain by multi-modal MRI and MRS measurements	57
	Dynamic nonlinearities in BOLD contrast: neuronal or hemodynamic?	73
	Oxygen delivery to the brain during behavioral activation at acute normobarie hypoxemia	87
	Quantitative aspects of changes in cerebral blood flow induced by neuronal activation	99
	Evoked cerebral blood flow is linear to neuronal activation but independent of metabolic oxygen demand	107
	Cortical blood flow through individual capillaries in rat vibrissa SI cortex: stimulus-induced changes in flow are comparable to the underlying fluctuations in flow	115
	Model of oxygen delivery to brain tissue in vivo explains beneficial effect of hypothermia in ischemia	123
	Neuronal activation induced changes in microcirculatory haemoglobin oxygenation: to dip or not to dip	137
	Spatio-temporal characteristics of neurovascular coupling in the anesthetized cat and the awake monkey	145
	Simultaneous measurements in brain tissue pO[subscript 2] and cerebral blood flow during functional stimulation	155
	Contribution of blood volume changes to intrinsic optical signals	165
	Sustained microvascular flow response to functional activation in rat cerebral cortex	173
	Quantitative optical imaging of brain activity - human and animal studies	181
	Role of astrocytes in coupling synaptic activity to glucose utilization	189
	The role of neuronal nitric oxide in the regional neurovascular coupling. Voxel-based comparison between perfusion and metabolic PET images	197
	Hemodynamic and metabolic features of cerebral activation	205
	Inhibition and functional magnetic resonance imaging	213
	Dynamic changes of CBF, CMRO[subscript 2], OEF, CMR[subscript glc], CBV and ADC during neuronal suppression due to hypothermia	223
	Cerebral metabolic compartmentation: the effects of hypothermia and metabolic activation	231
	Intrinsic optical recording of somatosensory responses in the human cerebral cortex during brain tumor surgery	243
	Activity-induced changes in cerebellar blood flow	251
	Neurovascular coupling in health and disease: lessons from transgenic mice	259
	Neuronal messengers as mediators of microvascular tone in the cerebral cortex	267
	The red blood cell, ATP and integrated vascular responses to neuronal stimulation	277
	Regulation of the cerebral circulation by cytochrome P450 epoxygenase activity	289
	Epoxyeicosatetrinoic acids released by astrocytes: function in cerebral angiogenesis	297
	Effects of activation of glutamate receptors on neurons and blood vessels	305
	The metabotropic glutamate receptor system: a novel pathway for the molecular protection against microvascular programmed cell death	313
	The Roy-Sherrington hypothesis: facts and surmises	325
	Adrenergic and cholinergic modulation of cerebrovascular nitrergic vasodilation	337
	Endothelium-derived hyperpolarizing factor in the cerebral circulation	347
	Variations in CBF during hypotension and in cortical eNOS in rats	357
	Neuronal nitric oxide synthase in the cerebrovascular endothelium	369
	Mechanisms of eGMP-induced cerebral vasodilatation contractile agonist and developmental age make a difference	379
	Impact of hormones on the regulation of cerebral vascular tone	395
	Unique aspects of NO-related cerebrovascular regulation: influence of estrogen and caveolin-I	401
	Effects of estrogen on the microcirculation and thrombus formation in pial vessels of the rat	413
	Imaging and preventing spreading depression independent of cerebral blood flow	421
	A time-variable concentric wave-ring increase in light transparency and associated microflow changes during a potassium-induced spreading depression in the rat cerebral cortex
	Real-time microcirculatory changes due to spreading depression under focal ischemia	449
	Functional activation of peri-infarct tissue for prediction of recovery after focal ischemia	457
	Ischemic depression of neuronal activity: real time comparison between DC potential changes and alterations of ion and transmitter homeostasis
	Ischemic energy failure and ions shifts are smaller and slower in white matter than in gray matter	475
	Temporal profile of gene induction after venous ischemia accompanied by spreading depression as compared to spreading depression alone	481
	Ischemia caused by inverse coupling between neuronal activation and cerebral blood flow in rats	487
	Tumor necrois factor-[alpha] heme oxygenase-I and manganese superoxide dismutase immunostaining of vessels and perivascular brain cells provides evidence for cyclic activation and inactivation of brain vessel segments	493
	Control of flow on the microvascular level	501
	Response of cerebral neocapillaries to acetylcholine: an intravital microscopic observation	509
	Imaging synchronization and propagation of intracellular calcium oscillation during non-synaptic seizure-like neuronal activity in rat	515
	Therapeutic efficacy of transcranial magnetic stimulation for amyotrophic lateral sclerosis and spinocerebellar degeneration	525
	Author index	533
	Keyword index	537