Molecular medicine Book

Chairman's Address. Preface. Gene diagnosis. Molecular genetics of the cutaneous basement membrane zone: clinical implications of basic research on epidermolysis bullosa (J. Uitto). Genetic Testing of Hearing Loss Disorders (W.J. Kimberling). Sensorineural hearing loss caused by the A1555G mutation in the mitochondrial DNA (S. Abe et al.). A mutation in plasma platelet-activating factor acetylhydrolase gene (G⁹⁹⁴ → T) is a genetic risk factor for stroke (K. Satoh et al.).Genotype-phenotype correlation of autosomal dominant retinal degenerations with mutations in the peripherin/RDS gene (M. Nakazawa et al.). Recent studies on DNA-based diagnosis for Japanese cases of dystrophic epidermolysis bullosa (K. Tamai et al.). A novel KIT gene missense mutation in a Japanese family with piebaldism (K. Nomura et al.). Genetic study for ossification of posterior longitudinal ligament of the spine (T. Numasawa et al.). Angiotensin converting enzyme gene polymorphism in lupus nephritis (H. Osawa et al.). CYP2D6 genotype and plasma levels of haloperidol and reduced haloperidol in Japanese ( T. Kondo et al.). Regulation of gene expression. Corticotropin-releasing hormone: new aspects of regulation and lessons from knockout mice (J.A. Majzoub). Regulation of hypothalamo-hypophyseal vasopressinergic neurons by glucocorticoids (M. Shoji et al.). Nrf1 and Nrf2 regulate ARE-mediated expression and coordinated induction of a battery of genes encoding proteins that protect cells against oxidative stress (A.K. Jaiswal). Pi-class glutathione tranferase expression and function in mouse neoplasia (S. Tsuchida et al.). Human small MAF proteins form hetrodimers with CNC family transcription factors and recognize the NF-E2 motif (E. Ito et al.). Approaches to intestinal &ggr;&dgr;т cells ( Y. Ishiguro, H. Kanazawa, A. Munakata). Metallothionein-null mouse exhibits reduced tolerance against ultraviolet-B injury in the skin (K. Hanada et al.). Gene structural similarity between hCRF-R1 and glucagon receptor family (K. Sakai et al.). Evaluation of CAR, Smad4, and KAI1 expression in colorectal tumors by a RT-PCR method (T. Mikami et al.). Cytokine expression and synthesis in oral squamous cell carcinoma (Y. Nakano et al.). Roles of cytokines in host defense to bacterial infections in mice (A. Nakane et al.). TGF-&bgr;/Smad and TNF-&agr;/NF-KB upregulate type VII collagen gene expression additively at the transcriptional level (A. Kon et al.). Expression of the apoptosis-related genes in colorectal cancers (H. Odagiri et al.). Primary structure and developmental state-specific expression of the mouse &ggr;-aminobutyraldehyde dehydrogenase (K. Ishii et al.). Gene therapy. Development of a novel in vivo gene delivery system for human gene therapy (Y. Kaneda). In vivo introduction of the interleukin 6 gene into keratinocytes (D. Sawamura et al.).

In vivo introducing cytokine genes into keratinocytes for approaching to cytekine gene therapy (X. Meng et al.). Index of authors. Keyword index.