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Epidemiology
Epidemiology of Osteoarthritis Lisa A. Mandl 1
Pathogenesis
The Role of Subchondral Bone in Osteoarthritis Johanne Martel-Pelletier Daniel Lajeunesse Pascal Reboul Jean-Pierre Pelletier 15
The Impact of Mechanical Stress on the Pathophysiology of Osteoarthritis George Nuki Donald Salter 33
Update on the Chondrocyte Lineage and Implications for Cell Therapy in Osteoarthritis Mary B. Goldring 53
Aging Cartilage and Osteoarthritis Cartilage: Differences and Shared Mechanisms Richard F. Loeser 77
Adipokines in Osteoarthritis Nathalie Presle Pascale Pottie Didier Mainard Patrick Netter Bernard Terlain 85
Pathology and Animal Models of Osteoarthritis Frank A. Wollheim L. Stefan Lohmander 104
Clinical Aspects
Biochemical Markers of Osteoarthritis Patrick Garnero 113
Radiographic Imaging in Osteoarthritis of the Hip and Knee Eric Vignon Marie-Pierre Hellio Le Graverand 131
Magnetic Resonance Imaging in Osteoarthritis Timothy Mosher 143
Treatment
Nonsteroidal Anti-inflammatory Drugs for Osteoarthritis DanielH. Solomon Nicola J. Goodson 178
Complementary and Alternative Medicine in Osteoarthritis Amanda Tiffany Lan X. Chen 202
Future Directions in Physical Therapy for Knee Osteoarthritis Kim Bennell Rana Hinman Tim Wrigley 217
Management of Limb Osteoarthritis Maxime Dougados 232
Nutritional and Nutritional Supplement Interventions for Osteoarthritis Timothy E. McAlindon Grace H. Lo 247
Index 267
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