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NMR Spectroscopy of Platinum Drugs: From DNA to Body Fluids | 1 | |
Trans-Diamminedichloroplatinum (II) Is Not an Antitumor Drug: Why? | 17 | |
Iminoethers as Carrier Ligands: A Novel trans-Platinum Complex Possessing in Vitro and in Vivo Antitumor Activity | 27 | |
Molecular Dynamics Simulations on Cisplatin Adducts with Dinucleotides | 37 | |
Orally Active DACH-Pt (IV) Compounds | 43 | |
Pharmacokinetic - Pharmacodynamic Relationships | 53 | |
Clinical Pharmacology of Carboplatin Administered in Alternating Sequence with Paclitaxel in Patients with Non-Small Cell Lung Cancer: A European Cancer Centre (ECC) Study | ||
The Clinical Development of the Oral Platinum Anticancer Agent JM216 | 83 | |
Membrane Transport of Platinum Compounds | 91 | |
Detection of Adducts Formed upon Treatment of DNA with Cisplatin and Carboplatin | 107 | |
Detection of Platinum Lesions at the Nucleotide Level in Cells using Single Strand Ligation PCR | 121 | |
A Review of the Modulation of Cisplatin Toxicities by Chemoprotectants | 131 | |
Combination Therapy with Cisplatinum and EGF Receptor Blockade | 155 | |
Oxaliplatin: Update on an Active and Safe Dach Platinum Complex | 165 | |
Combination of Different Platinum Compounds: Issues, Strategies and Experience | 175 | |
Phase I and II Studies with Lobaplatin | 181 | |
Phase I Trials of Ormaplatin (NSC 363812) | 187 | |
254-S, NK121 and TRK710 | 193 | |
Clinical Trials of Oxaliplatin and DWA2114R | 199 | |
Incorporating Assessments of Sequence-Dependence in Developmental Studies of Combination Chemotherapy Regimens Containing New Agents and Platinum Compounds | 205 | |
Review of Carboplatin-Based High-Dose Chemotherapy Combinations in the Autotransplant Setting | 221 | |
Treatment Intensification in Germ-Cell Tumours | 229 | |
IL-I[alpha] Enhancement of Platinum-Mediated Anti-Tumor Activity | ||
Overview of Tumor-Inhibiting Non-Platinum Complexes | 253 | |
The Cisplatin-Induced Cellular Injury Response | 269 | |
The Interaction of Cisplatin with Signal Transduction Pathways and the Regulation of Apoptosis | 283 | |
Cell Cycle Checkpoints and Cancer Chemotherapy | 293 | |
Carboplatin versus Cisplatin in the Chemotherapy of Solid Tumors: Pro-Carboplatin | 303 | |
Cisplatin and Carboplatin in Testis and Ovarian Cancer: Pro Cisplatin | 311 | |
Hypersensitivity to Cisplatin in Mouse Leukemia L1210/0 Cells: An XPG DNA Repair Defect | 317 | |
DNA Repair and the Carrier Ligand Specificity of Platinum Resistance | 327 | |
Transcription Factor Differences in Cisplatin Resistant Cells | 341 | |
Index | 347 |
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