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Preface | ||
Acknowledgments | ||
I | Introduction | 1 |
1 | Introduction to Transplantation in the Nervous System | 3 |
2 | Brain Structure and Development | 11 |
II | General and Background Information | 31 |
3 | History of Neural Transplantation | 33 |
4 | Transplants and How They Are Used | 45 |
5 | Control Groups and Experiments | 71 |
6 | Regulations and Guidelines for Fetal Tissue Transplantation | 81 |
7 | Mind Control and Other Things to Worry About | 91 |
III | Parkinson's Disease | 107 |
8 | Neural Systems and Parkinson's Disease | 109 |
9 | Neural Transplantation in Parkinson's Disease: A Brief Synopsis | 125 |
10 | Fetal Brain Tissue Transplantation in Parkinson's Disease: Experiments in Animals | 141 |
11 | Adrenal Medulla Transplantation | 169 |
12 | Studies in Subhuman Primates | 191 |
13 | Fetal Brain Tissue Transplantation in Parkinson's Disease: Clinical Studies | 201 |
IV | Using Transplants to Influence Localized Brain Functions | 241 |
14 | Pain | 243 |
15 | Hypothalamus and Pituitary | 259 |
16 | The Cerebral Cortex and Stroke | 273 |
V | Circuit Reconstruction | 287 |
17 | Huntington's Disease | 289 |
18 | Spinal Cord | 313 |
19 | Visual System | 361 |
VI | Genetic Engineering and Technology of the Future | 373 |
20 | Introduction to Genetic Engineering and Neural Transplantation | 375 |
21 | Growing Cells in Culture: Stem and Progenitor Cells | 387 |
22 | Growing Cells in Culture: Immortal Cell Lines | 399 |
23 | Genetically Modified Cells for Producing Neurotrophic Factors and Neurotransmitters | 425 |
24 | Direct Gene Transfer | 439 |
VII | Conclusions | 449 |
25 | Conclusions | 451 |
Glossary | 477 | |
References | 499 | |
Index | 543 |
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