Genetics of Bone Biology and Skeletal Disease Book

Part I: General Background to Bone Biology

1. Biology of Bone and Cartilage

2. Brendan Boyce, Michael Zuscik, Lianping Xing

3. Overview of Bone Structure and Strength

4. Mary L. Bouxsein

5. Overview of Joint and Cartilage Biology

6. Frank Luyten and Rik JU Lories

7. Integrating Endocrine and Paracrine Influences on Bone: Lessons from Parathyroid Hormone and Parathyroid Hormone-related Protein

8. T. John Martin and Natalie A. Sims

9. Energy Homeostasis and Neuronal Regulation of Bone Remodeling

10. Gerard Karsenty, Mathieu Ferron and Franck Oury

11. Neuropeptide Y and Bone Regulation

12. Paul A. Baldock

    Part II: General Background to Genetics

13. Genome-wide Association Studies

14. Matthew Brown and Emma L. Duncan

15. Genomic Profiling in Bone

16. Gabriela G. Loots and Bryan D. Hudson

17. Copy Number Variation

18. Hong-Wen Deng, Tie-Lin Yang, Yan Guo and Christopher J. Papasian

19. Prospects of Gene Therapy

20. Brendan Lee, Merry ZC Ruan and Kilian Guse

21. Pharmacogentics and Pharmacogenomics of Osteoporosis: Personalized Medicine Outlook

22. Tuan V. Nguyen and John A. Eisman

23. Genetic Testing & Counselling

24. Ingrid A. Holm, Christina M. Jacobsen, Yiping Shen and Stephanie J. Brewster

25. Mouse models: Approaches to Generating in vivo Models for Hereditary Disorders of Mineral and Skeletal Homeostasis

26. Sian E. Piret and Rajesh V. Thakker

27. Fetal Control of Calcium and Phosphate Homeostasis - Lessons from Mouse Models

28. Christopher S. Kovacs

29. Control of Skeletal Homeostasis during Pregnancy and Lactation - Lessons from Physiological Models

30. Christopher S. Kovacs

    Part III: Disorders of Bone and Joint

31. Osteogenesis Imperfecta

32. Joan Marini and M. Helen Rajpar

33. Osteoporosis Genes Identified by Genome-wide Association Studies

34. Andre Uitterlinden and Fernando Rivadenerira

35. Osteoarthritis - Genetic Studies of Monogenic and Complex Forms

36. Ana M. Valdes

37. Paget’s Disease

38. Stuart H. Ralston and Omar M.E. Albagha

39. Heritable Disorders of RANKL, OPG, RANK and NF-KB Signalling

40. Michael Whyte

41. Skeletal Dysplasias

42. William G. Cole

43. Hypophosphatasia

44. Michael P. Whyte

45. Sclerosing Bone Disorders

46. Bram Perdu and Wim Van Hul

47. Fibrodysplasia (Myositis) Ossificans Progressiva

48. Andria L. Culbert, Salin A. Chakkalakal, Michael R. Convente, Vitali Y. Lounev, Frederick S. Kaplan and Eileen M. Shore

    Part IV: Parathyroid and Related Disorders

49. Hyperparathyroidism

50. Andrew Arnold and Jessica Costa-Guda

51. Hypoparathyroidism

52. Rajesh V. Thakker

53. G_sa, Pseudohypoparathyroidism, Fibrous Dysplasia, and McCune-Albright Syndrome

54. Lee S. Weinstein, Allen M. Spiegel and Michael Collins

55. Genetic disorders affecting PTH/PTHrP receptor function

56. Harald Jueppner and Caroline Silve

57. Genetically Determined Disorders of the Calcium-Sensing Receptor

58. Edward M. Brown and Ogo I. Egbuna

59. Multiple Endocrine Neoplasia Type 1 (MEN1)

60. Rajesh V. Thakker

61. Multiple Endocrine Neoplasia Type 2 (MEN2)

62. Bruce Robinson, Rory Clifton-Bligh and Matti Gild

    Part V: Vitamin D and Renal Disorders

63. Heritable Renal Phosphate Wasting Disorders

64. Marc K. Drezner

65. Genetic Disorders of Vitamin D Synthesis and Action

66. David Feldman, Peter Malloy and Walter L. Miller

67. Renal Fanconi Syndrome, Dent's Disease and Bartter's Syndrome

68. Olivier Devuyst and Takashi Igarashi

69. Inherited Magnesium Disorders

70. Scott J. Schurman, Dhruval Patel, Anil Singh and Steven J. Scheinman

71. Genetic Hypercalciuria: A Major Risk Factor in Kidney Stones

David Bushinsky and Orson W. Moe