Practical Process Research and Development - A guide for Organic Chemists Book

Introduction Chapter 1. Introduction to the role of process development Chapter 2. Route selection Chapter 3. Reagent selection Chapter 4. Solvent selection Chapter 5. Running the reaction Chapter 6. Water as process consideration Chapter 7. In-process assays and in-process controls Chapter 8. Optimizing the reaction by minimizing impurity formation Chapter 9. Optimizing organometallic processes Chapter 10. Workup, chromatography, and preliminary purification Chapter 11. Purification, crystallization, and isolation Chapter 12. Final product form and impurities Chapter 13. Refining the process for simplicity, ruggedness & impurities Chapter 14. Continuous processing as an alternative to batch processing Chapter 15. Scale-up concerns and process implementation Chapter 16. Trouble-shooting Chapter 17. Trends and perspective Indices: reagent type, reaction type, and regular index including abbreviations.