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Part I. Central Nervous System
Section A. Metabolic Diseases – Hugo W. Moser
Chapter 1: Leukodystrophies
Chapter 2: Lysosomal Disorders of the Nervous System
Chapter 3: The Neurobiology of Peroxisomal Disorders
Chapter 4: Creatine Deficiency Syndromes
Section B. Neurodegenerative Disorders – Gregor Wenning
Chapter 5: Parkinson’s Disease
Chapter 6: Alzheimer Disease
Chapter 7: Multiple System Atrophy
Chapter 8: Olivopontocerebellar Atrophy (OPCA)
Chapter 9: Neurobiology of Progressive Supranuclear Palsy
Section C. Genetic Diseases – Christopher Gomez
Chapter 10: Protein Aggregation Disorders
Chapter 11: RNA-Based Disorders of Muscle and Brain
Chapter 12: Ion Channel Disorders
Chapter 13: Spinocerebellar Ataxia Type 1
Chapter 14: Shared Transcriptional Consequences of Mitochondrial Disease, Ischemic Hypoxia and Chemical Hypoxia
Section D. Neuroimmunological Disorders – Anthony T. Reder
Chapter 15: Paraneoplastic Neurological Disorders
Chapter 16: Systemic Lupus Erythematosus: Descriptive Past and Mechanistic Future
Chapter 17: Progressive Multifocal Leukoencephalopathy
Chapter 18: Multiple Sclerosis
Chapter 19: Immune-Mediated Neuropathies
Chapter 20: Hashimoto Encephalopathy
Section E. Cerebrovascular Diseases – Lewis Morgenstern
Chapter 21: Vascular Cognitive Impairment
Chapter 22: Cardioembolism
Chapter 23: Coagulation Disorders
Chapter 24: Clinical and Neurobiological Aspects of Stroke Recovery
Chapter 25: Non-Atherosclerotic Cerebral Vasculopathies
Chapter 26: Subarachnoid Hemorrhage
Chapter 27: Cerebral Ischemia: Molecular Mechanisms and Protective Therapies
Chapter 28: Intracerebral Hemorrhage and Intraventricular Hemorrhage-Induced Brain Injury
Section F. Paroxysmal Disorders – Timothy A. Pedley
Chapter 29: Idiopathic Epilepsies
Chapter 30: Paroxysmal Dyskinesia
Chapter 31: Neurobiology of Myoclonus
Chapter 32: Channelopathies of the Nervous System
Chapter 33: Migraine
Chapter 34: Temporal Lobe Epilepsy
Section G. Neoplastic Diseases – John Laterra
Chapter 35: CNS Metastases
Robert J. Weil
Chapter 36: Meningioma
Katrin Lamszus, Christian Hagel, and Manfred Westphal
Chapter 37: CNS Lymphoma
Corresponding Author: Dr. Batchelor
Chapter 38: Neurofibromatosis 1
Linda Piersall and David H. Gutmann
Chapter 39: Medulloblastoma and Primitive Neuroectodermal Tumors
Said Elshihabi and James T. Rutka
Chapter 40: Glioma
Anders I. Persson, QiWen Fan, Joanna J. Phillips, and William A. Weiss
Section H. Infectious Diseases – Richard T. Johnson
Chapter 41: Bacterial & Fungal
Chapter 42: Parasitic Infections
Chapter 43: Prion Diseases
Chapter 44: Central Nervous System Viral Infections: Clinical Aspects and Pathogenic Mechanisms
Section I. Motor Neuron Diseases – Eva L. Feldman
Chapter 45: Spinal Muscular Atrophy
Chapter 46: Amyotrophic Lateral Sclerosis-Like Syndromes Associated with Malignancy
Chapter 47: Amyotrophic Lateral Sclerosis (ALS): Idiopathic and Inherited
Chapter 48: Hereditary Spastic Paraplegia and Primary Lateral Sclerosis
Chapter 49: Poliomyelitis
Chapter 50: Spinobulbar Muscular Atrophy (Kennedy’s Disease)
Section J. Malformations and Developmental Disorders – Michael V. Johnston
Chapter 51: Neurobiology of Genetic Mental Retardation
Chapter 52: Cerebral Palsy
Chapter 53: Autism
Chapter 54: Neurobiology of Dyslexia
Chapter 55: Neonatal Brain Injuries
Chapter 56: Spina Bifida
Chapter 57: Circuits to Synapses: The Pathophysiology of Tourette Syndrome
Chapter 58: Attention Deficit Hyperactivity Disorder
Chapter 59: Congenital Hydrocephalus
Section K. Neurologic Manifestations of Medical Diseases – John J. Caronna
Chapter 60: Hematological Disorders
Chapter 61: Renal Disease
Chapter 62: Diabetes and Endocrine Disorders
Chapter 63: Mechanisms and Consequences of CNS Hypoxia
Chapter 64: Gastroenterologic and Hepatic Diseases and Their Effects on CNS
Chapter 65: Sarcoidosis
Section L. Sleep Disorders – Emmanuel Mignot
Chapter 66: REM Sleep Behavior Disorder
Chapter 67: The Neurobiology of Narcolepsy and Hypersomnia
Chapter 68: Restless Legs Syndrome and Periodic Leg Movement
Chapter 69: Obstructive Sleep Apnea
Chapter 70: The Neurobiology of Insomnia
Section M. Substance Abuse and Basic Toxicology – John C. M. Brust
Chapter 71: Organic Chemicals
Chapter 72: Metals
Chapter 73: Drug Addiction
Section N. Imaging the Nervous System – John C. Mazziotta
Chapter 74: Assessment of Neurobiological Diseases with Magnetic Resonance Spectroscopy
Chapter 75: Magnetic Resonance Imaging
Chapter 76: Neurovascular CT Angiography
Chapter 77: PET Imaging in Parkinson's Disease and Other Neurodegenerative Disorders
Chapter 78: Single Photon Emission Computed Tomography (SPECT)
Chapter 79: Functional Magnetic Resonance Imaging (fMRI)
Part II. Peripheral Nervous System
Section O. Peripheral Neuropathies – James Russell
Chapter 80: Diabetic and Metabolic Neuropathies
Chapter 81: Aquired Inflammatory Demyelinating and Axonal Neuropathies
Chapter 82: Toxic and Drug-Induced Neuropathies
Chapter 83: Hereditary Neuropathies
Chapter 84: Neurological Manifestations of Vasculitis
Chapter 85: Neuropathies Associated with Infections
Section P. Myopathies and neuromuscular junction disorders – Charles A. Thornton
Chapter 86: The Muscular Dystrophies
Chapter 87: Myasthenia Gravis and Myasthenic Syndromes
Chapter 88: Myopathies and Neuromuscular Junction Disorders
Chapter 89: Immunobiology of Autoimmune Inflammatory Myopathies
Section Q. Autonomic Disorders – Phillip A. Low
Chapter 90: Central Autonomic Network
Chapter 91: Autonomic Neuropathies
Chapter 92: Thermoregulation and its Disorders
Chapter 93: Control of Blood Pressure-Normal and Abnormal
Section R. Pain – Kenneth L. Casey
Chapter 94: Neoplasm-Induced Pain
Chapter 95: Pain Associated with the Autonomic Nervous System
Chapter 96: Post-Herpetic Neuralgia
Chapter 97: Central Post-Stroke Pain
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