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siRNA and miRNA Gene Silencing: From Bench to Bedside Book

siRNA and miRNA Gene Silencing: From Bench to Bedside
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siRNA and miRNA Gene Silencing: From Bench to Bedside, RNA interference has become a key method in the suppression of gene expression and the development of therapeutic agents, yet there is still the problem of delivery, stability, and the danger of off-target effects such as the silencing of unwanted genes a, siRNA and miRNA Gene Silencing: From Bench to Bedside
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  • siRNA and miRNA Gene Silencing: From Bench to Bedside
  • Written by author Mouldy Sioud
  • Published by Springer-Verlag New York, LLC, 5/26/2011
  • RNA interference has become a key method in the suppression of gene expression and the development of therapeutic agents, yet there is still the problem of delivery, stability, and the danger of off-target effects such as the silencing of unwanted genes a
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Authors

Methods for Selecting Effective siRNA Sequences by using Statistical and Clustering Techniques Shigeru Takasaki

Deciphering the Code of Innate Immunity Recognition of siRNAs

Mouldy Sioud

Peptide Targeted Delivery of Antisense Oligonucleotides and siRNAs into Mammalian Cells

Mouldy Sioud

Local and Systemic Delivery of siRNAs for Oligonucleotides Therapy

Fumitaka Takeshita, Naomi Hokaiwado, Kimi Honma, and Takahiro Ochiya

Imaging of siRNA Delivery and Silencing

Anna Moore and Zdravka Medarova

Recent Advances in Magnetofection and Its Potential to Deliver siRNAs in vitro

Olga Mykhaylyk, Olivier Zelphati, Edelburga Hammerschmid, Martina Anton, Joseph Rosenecker and Christian Plank

In vitro and in vivo Gene Silencing by Transkingdom RNAi (tkRNAi)

Shuanglin Xiang, Andrew C. Keates, Johannes Fruehauf, Youxin Yang, Hongnian Guo, Thu Nguyen, and Chiang J. Li

Bacterial Delivery of siRNAs: A New Approach to Solid Tumor Therapy

De-Qi Xu, Ling Zhang, Dennis J. Kopecko, Lifang Gao, Yueting Shao, Baofeng Guo, and Lijing Zhao

The Therapeutic Potential of LNA-modified siRNAs: Reduction of Off-target Effects by Chemical Modification of the siRNA Sequence

Kees Fluiter, Olaf R. F. Mook, and Frank Baas

pSM155 and pSM30 Vectors for miRNA and shRNA Expression

Junzhu Wu, Akua N. Bonsra, and Guangwei Du

Targeting Oncogenes with siRNAs

Olaf Heidenreich

Targeting Stromal-cancer Cell Interactions with siRNAs

Seyedhossein Aharinejad, Mouldy Sioud, Trevor Lucas, and Dietmar Abraham

Therapeutic Potential of siRNA-mediated Targeting of Urokinase Plasminogen Activator, Its Receptor, and Matrix Metalloproteinases

Christopher S. Gondi and Jasti S. Rao

Silencing of HIF-1a by RNA Interference in Human Glioma Cells in vitro and in vivo

David L. Gillespie, Jeannette R. Flynn, Brian T. Ragel, Maria Arce-Larreta, David A. Kelly, Sheryl R. Tripp, and Randy L. Jensen

RNA Interference-mediated Validation of Genes Involved in Telomere Maintenance and Evasion of Apoptosis as Cancer Therapeutic Targets

Marco Folini, Marzia Pennati, and Nadia Zaffaroni

Treating Respiratory Viral Diseases with Chemically Modified, Second Generation Intranasal siRNAs

Sailen Barik

Progress in the Therapeutic Applications of siRNAs against HIV-1

Miguel Angel Martínez

Protein Components of the microRNA Pathway and Human Diseases

Marjorie P. Perron and Patrick Provost

Intron-mediated RNA Interference and microRNA Biogenesis

Shao-Yao Ying and Shi-Lung Lin

Emergence of a Complex Relationship between HIV-1 and the microRNA Pathway

Dominique L. Ouellet, Isabelle Plante, Corinne Barat, Michel J. Tremblay, and Patrick Provost

Synthetic microRNA Targeting Glioma-associated Antigen-1 Protein

Naotake Tsuda, Takahi Mine, Constantin G. Ioannides, and David Z. Chang

Therapeutic Targeting of Gene Expression by siRNA Directed against BCR-ABL Transcripts in a Patient with Imatinib-resistant Chronic Myeloid Leukemia

Michael Koldehoff and Ahmet H. Elmaagacli


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siRNA and miRNA Gene Silencing: From Bench to Bedside, RNA interference has become a key method in the suppression of gene expression and the development of therapeutic agents, yet there is still the problem of delivery, stability, and the danger of off-target effects such as the silencing of unwanted genes a, siRNA and miRNA Gene Silencing: From Bench to Bedside

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siRNA and miRNA Gene Silencing: From Bench to Bedside, RNA interference has become a key method in the suppression of gene expression and the development of therapeutic agents, yet there is still the problem of delivery, stability, and the danger of off-target effects such as the silencing of unwanted genes a, siRNA and miRNA Gene Silencing: From Bench to Bedside

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siRNA and miRNA Gene Silencing: From Bench to Bedside, RNA interference has become a key method in the suppression of gene expression and the development of therapeutic agents, yet there is still the problem of delivery, stability, and the danger of off-target effects such as the silencing of unwanted genes a, siRNA and miRNA Gene Silencing: From Bench to Bedside

siRNA and miRNA Gene Silencing: From Bench to Bedside

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