Recombinant Protein Production with Prokaryotic & Eukaryotic Cells a Comparative View on Host Physiology Book

	List of Editors
	Foreword
	Protein synthesis and co-translational folding in cell-free translation systems	1
	The cellular response to unfolded proteins in the endoplasmic reticulum	17
	The effects of recombinant protein expression on the growth and metabolism of mammalian cells	29
	Mapping stresses in Escherichia coli to improve yield. Examining global gene regulation and 'cell conditioning' strategies	43
	Cellular responses to strong overexpression of recombinant genes in Escherichia coli: DNA relaxation and cell death after induction of a-glucosidase	55
	From Vitreoscilla hemoglobin (VHb) to a novel class of growth stimulating hemoglobin proteins	75
	Protein mass production in hybridomas and recombinant CHO cells	89
	Inducible gene copy number amplification for the production of heterologous proteins in Kluyveromyces lactis	99
	Antibiotic-free plasmid selection and maintenance in Bacteria	111
	Modelling of segregational plasmid instability of a recombinant strain suspension of Escherichia coli	125
	Production of optically pure aryl epoxides by recombinant E. coli carrying styrene monooxgenase: A new biocatalyst based on pseudomonas fluorescens ST genes	141
	Translational problems associated with the rare arginine CGG in Escherichia coli. Framshifting at CGG codons	151
	Optimisation of the solubility of the recombinant Itk kinase domain in Escherichia coli	159
	Bacterial senescence and the oxidation paradox	171
	Metabolic approaches for the optimisation of recombinant fermentation processes	179
	Control and optimisation of cellular bottlenecks in recombinant protein production	189
	Expression and fermentation strategies for recombinant protein production in Escherichia coli	195
	Overexpression of a Rhizopus oryzae lipase in Pichia pastoris strains containing multiple copies of the target gene	259
	Development of a heterologous gene expression system for use in Lactocossus lactis: A novel gram-positive expression system	269
	Metabolic network analysis for human therapeutic protein productions: effects of P/O ratio	277
	Process-oriented metabolic engineering: cell lines with new properties in nutrient exploitation and protein glycosylation	289
	Influence of the metabolic status of packaging cells on retroviral vector production	303
	Optimizing the production of recombinant prion protein from CHO cells	319
	Recombinant protein production by transient transfection of suspension-growing cells	331
	Production of recombinant human trypsinogen in Escherichia coli and Pichia pastoria: A comparison of expression systems	339
	Secretion of homologous and heterologous recombinant proteins in Escherichia coli and other gram-negative bacteria by using a new secretion system	347
	Monitoring of genes that respond to overproduction of insoluble recombinant proteins in Escherichia coli and Bacillus subtilis	359
	Model supported optimization of fed-batch fermentations for recombinant protein production	371
	Protease secretion capacity and performance analysis of recombinant Bacillus species	383
	Subject Index	393
	Authors Index	399