Pharmacogenetics of Psychotropic Drugs Book

	List of contributors
Pt. I	Introduction
1	Genes and psychopharmacology: exploring the interface	3
Pt. II	Clinical background and research design
2	From pharmacogenetics to pharmacogenomics of psychotropic drug response	21
3	Neuropsychopharmacology: the interface between genes and psychiatric nosology	36
4	Methodological issues in psychopharmacogenetics	57
5	Statistical approaches in psychopharmacogenetics	72
Pt. III	Molecular background
6	The psychopharmacogenetic-neurodevelopmental interface in serotonergic gene pathways	95
7	RNA processing regulation and interindividual variation	127
Pt. IV	Pharmacokinetics
8	Pharmacogenetics of psychotropic drug metabolism	157
9	Pharmacogenetics of chiral psychotropic drugs	181
Pt. V	Specific psychotropic drugs and disorders
10	Clozapine response and genetic variation in neurotransmitter receptor targets	217
11	Genetic factors underlying drug-induced tardive dyskinesia	245
12	Functional gene-linked polymorphic regions in pharmacogenetics	267
13	Alternative phenotypes and the pharmacogenetics of mood and anxiety disorders	283
14	Pharmacogenetics of anxiolytic drugs and the GABA-benzodiazepine receptor complex	300
15	Genetic factors and long-term prophylaxis in bipolar disorder	320
16	Genetic influences on responsiveness to anticonvulsant drugs	333
17	Apolipoprotein E as a marker in the treatment of Alzheimer's disease	360
18	Genetic variation and drug dependence risk factors	372
Pt. VI	Pharmacogenetics and brain imaging
19	Brain imaging and pharmacogenetics in Alzheimer's disease and schizophrenia	391
Pt. VII	Industry perspectives
20	Pharmacogenetics in psychotropic drug discovery and development	401
21	High-throughput single nucleotide polymorphism genotyping	420
	Index	439