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Molecular Principles of Fungal Pathogenesis Book

Molecular Principles of Fungal Pathogenesis
Molecular Principles of Fungal Pathogenesis, Molecular Principles of Fungal Pathogenesis presents readers with an up-to-date compendium of research in the field of medical mycology. This new volume measures the impact of genome projects, genetics, and molecular biology on the understanding of a dive, Molecular Principles of Fungal Pathogenesis has a rating of 3 stars
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Molecular Principles of Fungal Pathogenesis, Molecular Principles of Fungal Pathogenesis presents readers with an up-to-date compendium of research in the field of medical mycology. This new volume measures the impact of genome projects, genetics, and molecular biology on the understanding of a dive, Molecular Principles of Fungal Pathogenesis
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  • Molecular Principles of Fungal Pathogenesis
  • Written by author Joseph Heitman
  • Published by ASM Press, April 2006
  • Molecular Principles of Fungal Pathogenesis presents readers with an up-to-date compendium of research in the field of medical mycology. This new volume measures the impact of genome projects, genetics, and molecular biology on the understanding of a dive
  • Molecular Principles of Fungal Pathogenesis presents readers with an up-to-date compendium of research in the field of medical mycology. This new volume measures the impact of genome projects, genetics, and molecular biology on the understanding of a dive
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Authors

Contributors
Preface
IGeneral Principles
1Fungal Molecular Pathogenesis: What Can It Do and Why Do We Need It?3
2Sex, MAT, and the Evolution of Fungal Virulence13
3Postgenomic Strategies for Genetic Analysis: Insight from Saccharomyces cerevisiae and Candida albicans35
4Candida albicans Hypha Formation and Virulence45
5The Conversion from Classical Studies in Fungal Pathogenesis to the Molecular Era49
6Mating and Parasexual Genetics in Candida albicans71
7The Mating-Type Locus and Mating of Candida albicans and Candida glabrata89
8Evolution of Human-Pathogenic Fungi: Phylogenies and Species113
9Establishment of Cell Identity in Pathogenic Fungi133
10Signal Transduction in the Interactions of Fungal Pathogens and Mammalian Hosts143
11Function and Regulation of Adhesin Gene Families in Saccharomyces cerevisiae, Candida albicans, and Candida glabrata163
12Fungal Biofilms: Agents of Disease and Drug Resistance177
13Molecular Basis of Fungal Adherence to Endothelial and Epithelial Cells187
14Molecular Principles of Antifungal Drug Resistance197
IIModel Systems: Heterologous Hosts, Model Pathogens, and Fungal-Bacterial Interactions
15Heterologous Hosts and the Evolution and Study of Fungal Pathogenesis215
16Amoeba and Slime Mold: Hosts of Virulence Evolution227
17Aspergillus nidulans: a Model for Elucidation of Aspergillus fumigatus Secondary Metabolism235
18Saccharomyces cerevisiae: an Emerging and Model Pathogenic Fungus245
19Fungal-Bacterial Interactions261
20Amphibian Chytridiomycosis as an Emerging Infectious Disease of Wildlife: What Can We Learn from the Earliest Diverging Fungi?271
IIISpecific Pathogens
21Cryptococcus neoformans: a Sugar-Coated Killer281
22Toward a Molecular Understanding of Candida albicans Virulence305
23Molecular Determinants of Histoplasma capsulatum Pathogenesis321
24Molecular Determinants of Virulence in Aspergillus fumigatus333
25Pathogenesis of Pneumocystis347
26Virulence Mechanisms of Coccidioides
27Blastomyces dermatitidis Cell Surface Determinants and Their Application in Vaccine Development393
28Virulence Factors in Black Molds with Emphasis on Melanin, Chitin, and Wangiella as a Molecularly Tractable Model407
29Zygomycetes as Agents of Infectious Disease in Humans429
30Signaling Pathways in the Dimorphic Human Fungal Pathogen Penicillium marneffei441
IVThe Host
31Innate Humoral Immunity to Fungi457
32Innate and Acquired Cellular Immunity to Fungi471
33Acquired Antibody-Mediated Immunity to Fungi487
34Site-Specific Mucosal Immunity to Fungi: Lessons Learned from Candida albicans Applied to Other Fungi505
35Intracellular Pathogenesis of Histoplasma capsulatum527
36Interactions of Immune Cells with the Facultative Intracellular Pathogen Cryptococcus neoformans537
37Fungal Interactions with Leukocytes555
38Fungal Vaccine Development565
39Molecular Immunopathogenesis of Innate Host Defense against Chronic Disseminated (Hepatosplenic) Candidiasis583
VFuture Directions
40Studying Fungal Virulence by Using Genomics591
41Future of Functional Genomics of Histoplasma capsulatum611
42Functional Genomic Approaches to Fungal Pathogenesis, Drug Target Validation, and Antifungal Drug Discovery627
43Genetic and Proteomic Analysis of Fungal Virulence643
44Genomic Perspectives on the Fungal Kingdom657
Index667


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Molecular Principles of Fungal Pathogenesis, Molecular Principles of Fungal Pathogenesis presents readers with an up-to-date compendium of research in the field of medical mycology. This new volume measures the impact of genome projects, genetics, and molecular biology on the understanding of a dive, Molecular Principles of Fungal Pathogenesis

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Molecular Principles of Fungal Pathogenesis, Molecular Principles of Fungal Pathogenesis presents readers with an up-to-date compendium of research in the field of medical mycology. This new volume measures the impact of genome projects, genetics, and molecular biology on the understanding of a dive, Molecular Principles of Fungal Pathogenesis

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Molecular Principles of Fungal Pathogenesis, Molecular Principles of Fungal Pathogenesis presents readers with an up-to-date compendium of research in the field of medical mycology. This new volume measures the impact of genome projects, genetics, and molecular biology on the understanding of a dive, Molecular Principles of Fungal Pathogenesis

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