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This volume provides a compilation of the main principles of signal transduction mechanisms. The reader will become familiar with the most recent developments on:
- the structure and function of heterotrimeric G-proteins and their receptors;
- the small GTPases Ras, Rho, Rab and Arf;
- EGF receptor, Ca2+ and protein kinase C;
- phosphoinositide kinases (PI-3 kinases);
- phospholipases C and D;
- ceramides and possible modulators of apoptosis;
- transcription factors and gene activation;
- multidrug resistance transporters.
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