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Molecular Diversity In Drug Design Book

Molecular Diversity In Drug Design
Molecular Diversity In Drug Design, , Molecular Diversity In Drug Design has a rating of 3 stars
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Molecular Diversity In Drug Design, , Molecular Diversity In Drug Design
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  • Molecular Diversity In Drug Design
  • Written by author Philip M. Dean
  • Published by Springer Netherlands, October 1999
  • This book focuses on the theoretical problems associated with molecular diversity as it is being applied in the pharmaceutical industry. Therefore, this book deals with algorithms that are involved in understanding chemical space and selection of diverse
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Authors

Contributors
Acknowledgements
Preface
Issues in Molecular Diversity and the Role of Ligand Binding Sites1
Molecular Diversity in Drug Design. Application to High-Speed Synthesis and High-Throughput Screening23
Background Theory of Molecular Diversity43
Absolute vs Relative Similarity and Diversity67
Diversity in Very Large Libraries93
Subset-Selection Methods For Chemical Databases115
Molecular Diversity in Site-focused Libraries141
Managing Combinatorial Chemistry Information175
Design of Small Libraries for Lead Exploration197
The Design of Small- and Medium-sized Focused Combinatorial Libraries221
Index249


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