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Key Topics in Clinical Research Book

Key Topics in Clinical Research
Key Topics in Clinical Research, , Key Topics in Clinical Research has a rating of 4.5 stars
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Key Topics in Clinical Research, , Key Topics in Clinical Research
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Digital Copy
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  • Key Topics in Clinical Research
  • Written by author F. Gao Smith
  • Published by Informa Healthcare, June 2002
  • Key Topics in Clinical Research aims to provide a short, clear, highlighted reference to guide trainees and trainers through research and audit projects, from first idea, through to data collection and statistical analysis, to presentation and publication
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Authors

Contributors
Abbreviations
Preface
Medical research as part of post-graduate training1
Research process6
Research ideas9
Literature searching11
Laboratory research17
Research involving animals19
Volunteer studies23
Qualitative research26
Research design31
Randomization40
Conducting clinical trials44
Sample size and power50
Research ethics committees55
Grant application60
Data collection64
Measurements68
Descriptive and inferential statistics72
Types of data74
Summarizing data76
Measures of central tendency and dispersion83
The normal distribution89
Principles of statistical analysis - estimation and hypothesis testing99
Student's t test110
Wilcoxon matched pairs signed rank sum test124
Mann-Whitney U test128
Analysis of variance (ANOVA)133
Chi squared and Fisher's exact test140
Correlation and regression147
Logistic regression152
Survival data155
Choice of statistical methods164
Systemic review and meta-analysis167
Sensitivity and specificity171
Giving a presentation173
Writing up: case reports, publications and thesis176
Reference management180
Peer review185
Audit188
Risk adjustment and SMR193
ICNARC196
Protocol and guidelines200
Index202


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