Histone Deacetylases: Transcriptional Regulation and Other Cellular Functions Book

I. Class I Histone Deacetylases

Histone Deacetylase 1

Dominique Meunier and Christian Seiser

Biochemistry of Multiprotein HDAC Complexes

Alejandro Vaquero, Michael Scher, and Danny Reinberg

The Biology of HDAC3

Edward Seto

The Biology of HDAC8, a Unique Class I Histone Deacetylase

David Waltregny and Vincent Castronovo

II. Class II Histone Deacetylases

Regulation of Muscle Gene Expression by Histone Deacetylases

Timothy A. McKinsey and Eric N. Olson

The Class IIa Histone Deacetylases: Functions and Regulation

Herbert G. Kasler and Eric Verdin

Histone Deacetylases in the Response to Misfolded Proteins

J. Andrew McKee and Tso-Pang Yao

III. Class III Histone Deacetylases

Comparison of Sirtuin Sequences Between Archaea and Vertebrates

Roy A. Frye

Structure of the Sir2 Family of NAD+-Dependent Histone/Protein Deacetylases

Kehao Zhao and Ronen Marmorstein

The Enzymology of SIR2 Proteins

Margie T. Borra and John M. Denu

The Class III Protein Deacetylases: Homologs of Yeast Sir2p

Bjoern Schwer, Brian J. North, Nidhi Ahuja, Brett Marshall, and Eric Verdin

IV. Histone Deacetylase Inhibitors

HDAC Inhibitors: Discovery, Development, and Clinical Impacts

Akihiro Ito, Norikazu Nishino, and Minoru Yoshida

Cell Cycle Targets of Histone Deacetylase Inhibitors

Brian Gabrielli

HDAC Inhibitors: An Emerging Anticancer Therapeutic Strategy

Paul Kwon, Meier Hsu, Dalia Cohen, and Peter Atadja

Index