Harper's biochemistry Book

	Preface
1	Biochemistry and Medicine	1
2	Biomolecules and Biochemical Methods	6
3	Water and pH	15
Sect. I	Structures & Functions of Proteins & Enzymes	27
4	Amino Acids	27
5	Peptides	37
6	Proteins: Structure and Function	48
7	Proteins: Myoglobin and Hemoglobin	63
8	Enzymes: General Properties	74
9	Enzymes: Kinetics	86
10	Enzymes: Mechanisms of Action	103
11	Enzymes: Regulation of Activities	110
Sect. II	Bioenergetics & the Metabolism of Carbohydrates & Lipids	123
12	Bioenergetics: The Role of ATP	123
13	Biologic Oxidation	130
14	The Respiratory Chain and Oxidative Phosphorylation	137
15	Carbohydrates of Physiologic Significance	149
16	Lipids of Physiologic Significance	160
17	Overview of Intermediary Metabolism	172
18	The Citric Acid Cycle: The Catabolism of Acetyl-CoA	182
19	Glycolysis and the Oxidation of Pyruvate	190
20	Metabolism of Glycogen	199
21	Gluconeogenesis and Control of the Blood Glucose	208
22	The Pentose Phosphate Pathway and Other Pathways of Hexose Metabolism	219
23	Biosynthesis of Fatty Acids	230
24	Oxidation of Fatty Acids: Ketogenesis	238
25	Metabolism of Unsaturated Fatty Acids and Eicosanoids	250
26	Metabolism of Acylglycerols and Sphingolipids	259
27	Lipid Transport and Storage	268
28	Cholesterol Synthesis, Transport, and Excretion	285
29	Integration of Metabolism and the Provision of Tissue Fuels	298
Sect. III	Metabolism of Proteins & Amino Acids	307
30	Biosynthesis of the Nutritionally Nonessential Amino Acids	307
31	Catabolism of Proteins and of Amino Acid Nitrogen	313
32	Catabolism of the Carbon Skeletons of Amino Acids	323
33	Conversion of Amino Acids to Specialized Products	347
34	Porphyrins and Bile Pigments	359
Sect. IV	Structure, Function, & Replication of Informational Macromolecules	375
35	Nucleotides	375
36	Metabolism of Purine and Pyrimidine Nucleotides	386
37	Nucleic Acid Structure and Function	402
38	DNA Organization, Replication, and Repair	412
39	RNA Synthesis, Processing, and Modification	435
40	Protein Synthesis and the Genetic Code	452
41	Regulation of Gene Expression	468
42	Recombinant DNA Technology	488
Sect. V	Biochemistry of Extracellular & Intracellular Communication	505
43	Membranes: Structure, Assembly, and Function	505
44	Hormone Action	534
45	Pituitary and Hypothalamic Hormones	550
46	Thyroid Hormones	561
47	Hormones That Regulate Calcium Metabolism	567
48	Hormones of the Adrenal Cortex	575
49	Hormones of the Adrenal Medulla	588
50	Hormones of the Gonads	594
51	Hormones of the Pancreas and Gastrointestinal Tract	610
Sect. VI	Special Topics	627
52	Structure and Function of the Water-Soluble Vitamins	627
53	Structure and Function of the Lipid-Soluble Vitamins	642
54	Nutrition	653
55	Digestion and Absorption	662
56	Glycoproteins	675
57	The Extracellular Matrix	695
58	Muscle and the Cytoskeleton	715
59	Plasma Proteins, Immunoglobulins, and Blood Coagulation	737
60	Red and White Blood Cells	763
61	Metabolism of Xenobiotics	780
62	Cancer, Cancer Genes, and Growth Factors	787
63	Biochemical and Genetic Bases of Disease	812
64	The Biochemical Basis of Some Neuropsychiatric Disorders	829
65	Biochemical Case Histories	850
	Appendix	867
	Abbreviations	873
	Index	877