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Pt. I A Matter of the Heart 1
Ch. 1 Cholesterol Drugs Are Unnecessary 3
Ch. 2 Industry Is More Interested in "Me-Too" Drugs Than in Innovation 13
Ch. 3 It Takes Industry Too Long to Discover New Drugs 23
Pt. II The Role of Pharmaceutical R&D in Health Care 39
Ch. 4 Drugs Are Discovered by Academia 41
Ch. 5 New Medicines Add Costs But Little Benefit 50
Ch. 6 Big Pharma Has Failed and Should Learn from Biotech Success 59
Pt. III The Profit Motive 69
Ch. 7 The Industry Invents Diseases 71
Ch. 8 New Drugs Are Less Safe Than Traditional Medicines 79
Ch. 9 Industry Spends More on Advertising Than on R&D 91
Ch. 10 Industry Does Not Care About Diseases of the Developing World 100
Pt. IV The Future 109
Ch. 11 Big Pharma's Day Has Passed 111
Ch. 12 Final Reflections 122
References 124
Index 133
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