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List of Contributors | ||
Introduction | ||
1 | P-Glycoprotein-Mediated Multidrug Resistance: Experimental and Clinical Strategies for its Reversal | 3 |
2 | Multidrug Resistance Associated with Overexpression of MRP | 39 |
3 | Mechanisms of Resistance to Alkylating Agents | 65 |
4 | Glutathione S-Transferases | 83 |
5 | Role of DNA Repair in Resistance to Drugs that Alkylate O[superscript 6] of Guanine | 123 |
6 | Paclitaxel (Taxol): Mechanisms of Resistance | 149 |
7 | Mechanisms of Clinical Resistance to 5-Fluorouracil Chemotherapy | 175 |
8 | Antifolates: Current Developments | 197 |
9 | Human Immunodeficiency Virus Replication in the Presence of Antiretroviral Drugs: Analogies to Antineoplastic Drug Resistance | 225 |
10 | Cellular Resistance to Topoisomerase Poisons | 243 |
11 | Acquisition of an Antiestrogen Resistant Phenotype in Breast Cancer: Role of Cellular and Molecular Mechanisms | 263 |
12 | Androgen Receptor Mutations in Prostate Cancer | 285 |
13 | Retinoids in Clinical Cancer Therapy | 305 |
14 | Apoptosis and Cancer Chemotherapy | 345 |
15 | Interaction of Chemotherapy and Biological Response Modifiers in the Treatment of Melanoma | 357 |
16 | Multifunctional Modulators of Drug Resistance | 381 |
Index | 409 |
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Add Drug Resistance, Resistance to treatment represents the final common outcome for far too many patients with cancer. Even our most promising new drugs fall victim to drug resistance. Hormones and newer biological therapies, though safe and active, also lose their activity , Drug Resistance to the inventory that you are selling on WonderClubX
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Add Drug Resistance, Resistance to treatment represents the final common outcome for far too many patients with cancer. Even our most promising new drugs fall victim to drug resistance. Hormones and newer biological therapies, though safe and active, also lose their activity , Drug Resistance to your collection on WonderClub |