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Part I. Historical Perspectives
Dietary Fatty Acids, COX-2 Blockade, and Carcinogenesis
Rashida A. Karmali
Historical Aspects of COX-2: Cloning and Characterization of the cDNA, Protein and Gene
Harvey R. Herschman
Part II. Epidemiology of NSAIDs and Cancer
Epidemiology of Nonsteroidal Anti-Inflammatory Drugs and Colorectal Cancer
Michael J. Thun and S. Jane Henley
Epidemiology of Breast Cancer and Nonsteroidal Anti-Inflammatory Drugs: Extension of the Dietary Fat Hypothesis of Breast Cancer
Randall E. Harris
Part III. Animal Models of Carcinogenesis
Role of Synthetic and Naturally Occurring Cyclooxygenase Inhibitors in Colon Cancer Prevention
Bandaru S. Reddy and Chinthalapally V. Rao
Chemoprevention of Breast Cancer by Nonsteroidal Anti-Inflammatory Drugs and Selective COX-2 Blockade in Animals
Hussein M. Abou-Issa, Galal A. Alshafie, and Randall E. Harris
The Role of Cyclooxygenase-2 in the Prevention and Therapy of Lung Cancer
Hildegard M. Schuller
Nonsteroidal Anti-Inflammatory Drugs, Prostaglandins, and Apc-Driven Intestinal Tumorigenesis
Jay Whelan and Michael F. McEntee
Cyclooxygenase-1 and Cyclooxygenase-2 Knockout Mice Provide Insights into Beneficial and Adverse Effects of Nonsteroidal Anti-Inflammatory Drugs
Robert Langenbach
Part IV. Molecular Biology of COX-2
Cyclooxygenase-2, Prostaglandins, and Colorectal Carcinogenesis
Rajnish A. Gupta and Raymond N. DuBois
Regulation of Expression and Potential Carcinogenic Role of Cyclooxygenase-2
Byeong-Churl Jang and Timothy Hla
Cyclooxygenase-2 and Cancer
Alane T. Koki, Kathleen M. Leahy, Janet M. Harmon, and Jaime L. Masferrer
Interactions of Cyclooxygenase and Aromatase Pathways in Normal and Malignant Breast Cells
Jeanette A. Richards and Robert W. Brueggemeier
Association of COX-2 and PPARs in Carcinogenesis and Chemoprevention
Tong-Chuan He
Carcinogenesis Involving Cyclooxygenase and Lipoxygenase
Linda C. Hsi and Thomas E. Eling
Part V. Clinical Applications
The Development of Drugs that Target Cyclooxygenase-2
Timothy Maziasz, K. Nasir Khan, John Talley, James Gierse, and Karen Seibert
Chemoprevention of Cancer by NSAIDs and Selective COX-2 Blockade
Gary J. Kelloff, Vernon E. Steele, and Caroline C. Sigman
Potential for Inhibitors of Cyclooxygenase-2 to Enhance Tumor Radioresponse
Randy Burd, Hak Choy, and Adam Dicker
Potential Role of NSAIDs and COX-2 Blockade in Cancer Therapy
William F. Anderson, Asad Umar, Jaye L. Viner, and Ernest T. Hawk
Cyclooxygenase-2 Blockade in Cancer Prevention and Therapy: Widening the Scope of Impact
Randall E. Harris
Index
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Add COX-2 Blockade in Cancer Prevention and Therapy, This book chronicles the evidence for the chemopreventive and therapeutic effects of cyclooxygenase-2 (COX-2) inhibitors against virtually all forms of cancer and presents exciting new opportunities for the use of COX-2 blockade in its prevention and trea, COX-2 Blockade in Cancer Prevention and Therapy to the inventory that you are selling on WonderClubX
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Add COX-2 Blockade in Cancer Prevention and Therapy, This book chronicles the evidence for the chemopreventive and therapeutic effects of cyclooxygenase-2 (COX-2) inhibitors against virtually all forms of cancer and presents exciting new opportunities for the use of COX-2 blockade in its prevention and trea, COX-2 Blockade in Cancer Prevention and Therapy to your collection on WonderClub |