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Clinical Trials for the Treatment of Sepsis Book

Clinical Trials for the Treatment of Sepsis
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Clinical Trials for the Treatment of Sepsis, The incidence of sepsis is increasing as new medical and surgical technologies are applied to an increasingly aging patient population. The treatment of sepsis emphasizes strategies to avoid multiple organ dysfunction, with particular attention to establi, Clinical Trials for the Treatment of Sepsis
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  • Clinical Trials for the Treatment of Sepsis
  • Written by author J. L. Vincent, William J. Sibbald
  • Published by Springer-Verlag Berlin and Heidelberg GmbH & Co. K, 1994/12/01
  • The incidence of sepsis is increasing as new medical and surgical technologies are applied to an increasingly aging patient population. The treatment of sepsis emphasizes strategies to avoid multiple organ dysfunction, with particular attention to establi
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Clinical Trials in the Treatment of Sepsis: An Evidence-Based Approach
The Systemic Inflammatory Response Syndrome (SIRS) 3
The "At Risk" Patient Population 13
Outcome and Prognostic Factors in Bacteremic Sepsis 35
ARDS and Sepsis: Resemblances and Differences 52
Microbiological Requirements for Studies of Sepsis 71
Measurement of Inflammatory Mediators in Clinical Sepsis 86
Whole Body and Organ Measures of O[subscript 2] Availability 106
Multiple Organ Dysfunction Syndrome (MODS) 122
What Determines Prognosis in Sepsis? 141
SAPS II and MPM II Models for Early Severe Sepsis 157
Fluid Therapy in Septic Shock 167
Role of RBC Transfusion Therapy in Sepsis 191
Vasoactive Drug Therapy in Sepsis 207
Evidence-Based Analysis of Nutrition Support in Sepsis 225
Anti-Endotoxin Therapy 237
Critical Reappraisal of Steroids and Other Anti-Inflammatory Agents 251
Investigational Therapy of Sepsis: Anti-TNF, IL-Ira. Anti-PAF and G-CSF 267
Sepsis and Acute Lung Injury 283
Increasing Oxygen Delivery in Sepsis 299
Critical Evaluation of the Design and Conduct of Previous Clinical Trials in Sepsis 317
Evaluation of the Adequacy of Source Control 329
Statistical Considerations for the Design of the Optimal Clinical Trial 345
The Monitoring and Reporting of Clinical Trials 354
Economic Evaluation in the Critical Care Literature 370
Ethical Issues in Clinical Trials 386
Subject Index 403


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Clinical Trials for the Treatment of Sepsis, The incidence of sepsis is increasing as new medical and surgical technologies are applied to an increasingly aging patient population. The treatment of sepsis emphasizes strategies to avoid multiple organ dysfunction, with particular attention to establi, Clinical Trials for the Treatment of Sepsis

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Clinical Trials for the Treatment of Sepsis, The incidence of sepsis is increasing as new medical and surgical technologies are applied to an increasingly aging patient population. The treatment of sepsis emphasizes strategies to avoid multiple organ dysfunction, with particular attention to establi, Clinical Trials for the Treatment of Sepsis

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