Challenges in Growth Hormone Therapy Book

	List of contributors
	Foreword
	Preface
Pt. 1	GH Replacement in Childhood
1	GH replacement in children: what is the optimum dosing schedule?	3
2	What is the current status of GH therapy in children with Turner syndrome?	19
3	Is there a role for GH therapy in Noonan syndrome?	36
4	Does GH therapy influence final height in skeletal dysplasia syndromes?	54
5	Is there a role for GH therapy in short normal children?	64
6	What is the role of GH therapy in children born small for gestational age?	78
Pt. 2	GH Replacement in Hypopituitary Adults
7	Is cardiovascular mortality increased in hypopituitary adults?	93
8	How should we diagnose GH deficiency in hypopituitary adults?	106
9	What is the impact of GH deficiency on bone density in childhood-onset and adult-onset GH deficiency, and how effective is GH replacement?	123
10	Individual susceptibility and GH dosing regimen in adults	143
11	What is the impact of GH deficiency and GH replacement on quality of life in childhood-onset and adult-onset GH deficiency?	160
12	Is there an upper age limit for GH replacement in hypopituitary adults?	177
13	Is open-ended GH replacement a safe therapy?	191
Pt. 3	Adolescent-adult Transition
14	How should we evaluate GH-treated patients at completion of linear growth?	211
15	How should we transfer patients from paediatric to adult clinics?	222
Pt. 4	Non-classical Uses of Growth Hormone
16	Is there a role for GH therapy in osteoporosis and in ageing?	235
17	What is the current status of GH therapy in catabolic adults?	255
18	Is GH therapy indicated in the metabolic syndrome?	264
19	Does GH therapy have a role in the management of cardiac failure?	282
	Index	291