Cell Activation and Apoptosis in HIV Infection: Implications for Pathogenesis and Therapy Book

1	CD4+ and CD8+ T Lymphocyte Activation in HIV Infection: Implications for Immune Pathogenesis and Therapy	1
2	Markers of Immune Cell Activation and Disease Progression: Cell Activation in HIV Disease	17
3	The Role of the Cell Cycle in HIV-1 Infection	27
4	Molecular Basis of Cell Cycle Dependent HIV-1 Replication: Implications for Control of Virus Burden	33
5	Regulation of Macrophage Activation and HIV Replication	47
6	Investigations on Autologous T-Cells for Adoptive Immunotherapy of AIDS	57
7	Rational Problems Associated with the Development of Cellular Approaches in Controlling HIV Spread	71
8	The Role of Surface CD4 in HIV-Induced Apoptosis	91
9	Mechanism of Apoptosis in Peripheral Blood Mononuclear Cells of HIV-Infected Patients	101
10	Programmed Death of T Cells in the Course of HIV Infection	115
11	T Cell Apoptosis as a Consequence of Chronic Activation of the Immune System in HIV Infection	121
12	Apoptosis during HIV Infection: A Cytopathic Effect of HIV or an Important Host-Defense Mechanism against Viruses in General?	129
13	From Cell Activation to Cell Depletion: The Programmed Cell Death Hypothesis of AIDS Pathogenesis	139
14	Immunosuppression by a Noncytolytic Virus Via T Cell Mediated Immunopathology: Implication for AIDS	165
15	Clonal Expansion of T Cells and HIV Genotypes in Microdissected Splenic White Pulps Indicates Viral Replication in Situ and Infiltration of HIV-Specific Cytotoxic T Lymphocytes	173
16	Autoimmunity, Apoptosis Defects, and Retroviruses	183
17	AIDS as Immune System Activation: Key Questions that Remain	203
18	Inhibition of T Lymphocyte Activation and Apoptotic Cell Death by Cyclosporin A and Tacrolimus (FK506): Its Relevance to Therapy of HIV Infection	211
19	Cyclophilin and Gag in HIV-1 Replication and Pathogenesis	217
20	Long-Term Follow-up of HIV Positive Asymptomatic Patients Having Received Cyclosporin A	229
21	Prospective Views of HIV Pathology: Clues for Therapeutic Strategies	235
	Index	243