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Macrolide Antibiotics Book

Macrolide Antibiotics
Macrolide Antibiotics, , Macrolide Antibiotics has a rating of 3 stars
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  • Macrolide Antibiotics
  • Written by author W. Sch nfeld
  • Published by Springer-Verlag New York, LLC, October 2007
  • The current state of research, development, and use of macrolides as a treatment option for bacterial infections is the subject of this monograph. Macrolides, whose first representative (erythromycin) was introduced into the market in the 1950s, have been
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Authors

List of Contributors
Preface
Introduction to the macrolide antibiotics1
Macrolides: a clinical overview15
Pharmacokinetics/pharmacodynamics of macrolides25
Cellular accumulation of macrolide antibiotics. Intracellular bioactivity37
Clarithromycin and new derivatives of erythromycin53
Azithromycin and novel azalides73
Ketolides: novel antibacterial agents designed to overcome resistance to erythromycin A within gram-positive cocci97
Novel macrolide derivatives active against resistance pathogens141
Polyketide diversity157
Biosynthesis of the macrolide antibiotic, tylosin177
In vitro activity of macrolides against traditional susceptible bacteria185
Activity of macrolides against mycobacteria201
Chlamydia pneumoniae and asthma and atherosclerosis: role of macrolides215
Activity of macrolides in sexually transmitted diseases229
Helicobacter pylori and macrolides243
Effects of macrolide antibiotics on ribosome function261
Mechanisms of resistance to macrolides, lincosamides, and ketolides281
Subject index319


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