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List of Contributors | ||
Preface | ||
Introduction to the macrolide antibiotics | 1 | |
Macrolides: a clinical overview | 15 | |
Pharmacokinetics/pharmacodynamics of macrolides | 25 | |
Cellular accumulation of macrolide antibiotics. Intracellular bioactivity | 37 | |
Clarithromycin and new derivatives of erythromycin | 53 | |
Azithromycin and novel azalides | 73 | |
Ketolides: novel antibacterial agents designed to overcome resistance to erythromycin A within gram-positive cocci | 97 | |
Novel macrolide derivatives active against resistance pathogens | 141 | |
Polyketide diversity | 157 | |
Biosynthesis of the macrolide antibiotic, tylosin | 177 | |
In vitro activity of macrolides against traditional susceptible bacteria | 185 | |
Activity of macrolides against mycobacteria | 201 | |
Chlamydia pneumoniae and asthma and atherosclerosis: role of macrolides | 215 | |
Activity of macrolides in sexually transmitted diseases | 229 | |
Helicobacter pylori and macrolides | 243 | |
Effects of macrolide antibiotics on ribosome function | 261 | |
Mechanisms of resistance to macrolides, lincosamides, and ketolides | 281 | |
Subject index | 319 |
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