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Biopharmaceuticals in Plants: Toward the Next Century of Medicine Book

Biopharmaceuticals in Plants: Toward the Next Century of Medicine
Biopharmaceuticals in Plants: Toward the Next Century of Medicine, Transgenic plants present enormous potential to become one of the most cost-effective and safe systems for large-scale production of proteins for industrial, pharmaceutical, veterinary, and agricultural uses. Over the past decade, much progress has been m, Biopharmaceuticals in Plants: Toward the Next Century of Medicine has a rating of 2.5 stars
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Biopharmaceuticals in Plants: Toward the Next Century of Medicine, Transgenic plants present enormous potential to become one of the most cost-effective and safe systems for large-scale production of proteins for industrial, pharmaceutical, veterinary, and agricultural uses. Over the past decade, much progress has been m, Biopharmaceuticals in Plants: Toward the Next Century of Medicine
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  • Biopharmaceuticals in Plants: Toward the Next Century of Medicine
  • Written by author Kathleen Laura Hefferon
  • Published by Taylor & Francis, Inc., November 2009
  • Transgenic plants present enormous potential to become one of the most cost-effective and safe systems for large-scale production of proteins for industrial, pharmaceutical, veterinary, and agricultural uses. Over the past decade, much progress has been m
  • Transgenic plants present enormous potential to become one of the most cost-effective and safe systems for large-scale production of proteins for industrial, pharmaceutical, veterinary, and agricultural uses. Over the past decade, much progress has been m
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Book Categories

Authors

History of Plants in Production of Biopharmaceuticals

History of Vaccine Development

History of Vaccine Proteins Produced in Plants

Transformation of Plant Tissue

Agrobacterium tumefaciens-Mediated Plant Transformation

Other Transformation Techniques

Problems Associated with Transformation Techniques

Transformation of Cereals

Hairy Root Transformation

Selectable Marker Genes

Regulation of Transgene Expression

Transgenic Plants Expressing Vaccine and Therapeutic Proteins

Transgenic Plants Expressing Vaccines against Diarrheal Diseases

Animal Vaccines Produced in Plants

The Use of Antibodies in Plants as Immunotherapeutic Agents

Other Biopharmaceuticals and Therapeutic Agents Produced in Plants

Enhancement of Plants for Nutritional or Medicinal Purposes (Nutriceuticals)

Chloroplast Engineering and Production of Biopharmaceuticals

Differences between Nuclear and Plastid Transformations

Plastid Transformation

History of Plastid Transformation and Biotechnological Applications

Vaccines and Therapeutic Proteins Produced in Chloroplasts

Plant Viral Expression Vectors and Production of Biopharmaceuticals in Plants

Plant RNA and DNA Virus Expression Systems

Glycosylation of Therapeutic Proteins in Plants

N-Glycosylation

Differences in N-Glycosylation Patterns between Plants and Mammals

Plant-Made Pharmaceuticals and Plant Allergens

Strategies to Humanize Recombinant Proteins in Plants

O-Glycosylation

Sialic Acid in Plants

Glycosylation of Immunoglobulins Produced in Plants

Other Therapeutic Proteins

Scale-Up of Plant-Derived Biopharmaceuticals: Prospects for Commercial Production and for Global Health

Plant-Made Biopharmaceuticals on the Market

Scale-Up and Production of Biopharmaceuticals in Plants

Application of Virus Expression Vectors for Large-Scale Field Trials

Production of Biopharmaceuticals in Plant Suspension Cells

Comparison of Cell Culture over Whole Plants for Biopharmaceutical Production

Other Expression Systems for Large-Scale Production of Biopharmaceuticals

Downstream Processing of Plant-Derived Biopharmaceuticals

Driving Forces behind Plant-Made Biopharmaceuticals: The General Market Environment

The Immune Response to Plant-Derived Pharmaceuticals

The Immune System in General

T Cells

B Cells

Antibodies and the Immune Response

The Concept of Vaccination and Immune Imprinting

Organization of the Mucosal Immune System

Secretory IgA and the Mucosal Epithelium

Mucosal Immune Response of the Respiratory Tract

Oral Tolerance

Preclinical and Clinical Trials Involving Plant-Derived Vaccines

Diarrheal Diseases

Hepatitis B Virus (HBV)

Rabies Virus

Human Papillomavirus (HPV)

Anthrax

Severe Acute Respiratory Syndrome (SARS)

Measles Virus

Influenza Virus

Swine-Transmissible Gastroenteritis Virus

Canine Parvovirus

Oral Tolerance to Antigens

Risk Analysis and Safety of Plant-Made Biopharmaceuticals

Risk Analysis and Plant-Based Biopharmaceuticals

Regulation of Plant-Made Biopharmaceuticals

Quality Control and the Manufacturing of the Product

Impact of Plant-Made Biopharmaceuticals on Human Health

Impact of Plant-Made Biopharmaceuticals on the Environment

Avoiding Transgene Silencing

Epilogue: The Future

The Current State of Plant-Made Biopharmaceuticals

Index


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Biopharmaceuticals in Plants: Toward the Next Century of Medicine, Transgenic plants present enormous potential to become one of the most cost-effective and safe systems for large-scale production of proteins for industrial, pharmaceutical, veterinary, and agricultural uses. Over the past decade, much progress has been m, Biopharmaceuticals in Plants: Toward the Next Century of Medicine

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Biopharmaceuticals in Plants: Toward the Next Century of Medicine, Transgenic plants present enormous potential to become one of the most cost-effective and safe systems for large-scale production of proteins for industrial, pharmaceutical, veterinary, and agricultural uses. Over the past decade, much progress has been m, Biopharmaceuticals in Plants: Toward the Next Century of Medicine

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Biopharmaceuticals in Plants: Toward the Next Century of Medicine, Transgenic plants present enormous potential to become one of the most cost-effective and safe systems for large-scale production of proteins for industrial, pharmaceutical, veterinary, and agricultural uses. Over the past decade, much progress has been m, Biopharmaceuticals in Plants: Toward the Next Century of Medicine

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